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Serpina3b Gene Detail
Summary
  • Symbol
    Serpina3b
  • Name
    serine (or cysteine) peptidase inhibitor, clade A, member 3B
  • Synonyms
    6A1, A030003A19Rik, alpha-1 antiproteinase, antitrypsin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2182835
    NCBI Gene: 271047
Location & Maps
more
  • Sequence Map
    Chr12:104127996-104139545 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11550 bp   ±  kb flank

  • Genome Browsers
Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Serpina3b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027589 VEGA Gene Model | MGI Sequence Detail 11550 C57BL/6J ±  kb
transcript OTTMUST00000068302 VEGA | MGI Sequence Detail 2070 Not Applicable  
polypeptide OTTMUSP00000034498 VEGA | MGI Sequence Detail 420 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    236 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
Other
Accession IDs
less
MGI:3045329
References
more
  • Summaries
    All 20
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:82699 Forsyth S, et al., A review and comparison of the murine alpha(1)-antitrypsin and alpha(1)-antichymotrypsin multigene clusters with the human clade A serpins. Genomics. 2003 Mar;81(3):336-45
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory