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Serpina3b
Gene Detail
Symbol

Name
ID
Serpina3b
serine (or cysteine) peptidase inhibitor, clade A, member 3B
MGI:2182835
Synonyms
6A1, A030003A19Rik, alpha-1 antiproteinase, antitrypsin
Feature Type
protein coding gene
Genetic Map
Chromosome 12
53.40 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:104127996-104139545 bp, + strand
From VEGA annotation of GRCm38

  11550 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:120222  Vertebrate Homology Class
2 mouse; 1 rat

Protein SuperFamily: serpin
Gene Tree: Serpina3b

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpina3b interacts with 117 markers (Mir18, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000027589 (Evidence)
Ensembl Gene ModelENSMUSG00000066364 (Evidence)
Entrez Gene271047 (Evidence)
UniGene120265
DFCITC1593686
DoTSDT.94148296
NIA Mouse Gene IndexU119116
Consensus CDS ProjectCCDS26147.1
International Mouse Knockout Project StatusSerpina3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027589 VEGA Gene Model | MGI Sequence Detail 11550 C57BL/6J ±  kb
transcript OTTMUST00000068302 VEGA | MGI Sequence Detail 2070 Not Applicable 
polypeptide OTTMUSP00000034498 VEGA | MGI Sequence Detail 420 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(234 from dbSNP Build 137)    SNPs within 2kb including multiple locations(236)
Protein-related
information
ResourceIDDescription
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000015934 serine protease inhibitor A3B
References
(Earliest) J:82699 Forsyth S, et al., A review and comparison of the murine alpha(1)-antitrypsin and alpha(1)-antichymotrypsin multigene clusters with the human clade A serpins. Genomics. 2003 Mar;81(3):336-45
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(24)
Other
accession IDs
MGI:3045329

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory