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Il23r
Gene Detail
 Symbol
Name
ID
Il23r
interleukin 23 receptor
MGI:2181693
Feature Type protein coding gene
Genetic Map
Chromosome 6
30.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:67422932-67491855 bp, - strand
From VEGA annotation of GRCm38

  68924 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16930  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Il23r

Human
homologs
Human Homolog IL23R, interleukin 23 receptor
NCBI Gene ID 149233
neXtProt AC  NX_Q5VWK5
Human Chr (Location)  1p31.3; chr1:67138907-67259979 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human IL23R
Alleles
and
phenotypes
All alleles(8) : Targeted(8)
Incidental mutations (data from Mutagenetix , APF )
 
Th17 T cells from homozygous null mice have less secretion of IL-9 upon secondary stimulation.
 
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process cytokine-mediated signaling pathway, immune system process, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function interleukin-12 receptor binding, interleukin-23 binding, ...
External Resources: FuncBase
Expression
cDNA source data(2)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(2) cDNA(2)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000029859 (Evidence)
Ensembl Gene ModelENSMUSG00000049093 (Evidence)
Entrez Gene209590 (Evidence)
UniGene221227
DoTSDT.101349629
NIA Mouse Gene IndexU027413
Consensus CDS ProjectCCDS39503.2
International Mouse Knockout Project StatusIl23r
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029859 VEGA Gene Model | MGI Sequence Detail 68924 C57BL/6J ±  kb
transcript OTTMUST00000074102 VEGA | MGI Sequence Detail 2488 Not Applicable 
polypeptide OTTMUSP00000038453 VEGA | MGI Sequence Detail 659 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(415 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR015321 Interleukin-6 receptor alpha chain, binding
Protein Ontology PR:000009001 interleukin-23 receptor
References (Earliest) J:76845 Parham C, et al., A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. J Immunol. 2002 Jun 1;168(11):5699-708
(Latest) J:200526 Laird RM, et al., gammadelta T cells acquire effector fates in the thymus and differentiate into cytokine-producing effectors in a listeria model of infection independently of CD28 costimulation. PLoS One. 2013;8(5):e63178
All references(44)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory