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Adamts14 Gene Detail
Summary
  • Symbol
    Adamts14
  • Name
    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14
  • Synonyms
    Adamts-14, TS14
  • Feature Type
    protein coding gene
  • IDs
    MGI:2179942
    NCBI Gene: 237360
Location & Maps
more
  • Sequence Map
    Chr10:61197112-61273438 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      76327 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 32.16 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ADAMTS14, ADAM metallopeptidase with thrombospondin type 1 motif 14
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ADAMTS14, ADAM metallopeptidase with thrombospondin type 1 motif 14
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 140766
    neXtProt AC: NX_Q8WXS8

  • Chr Location
    10q21; chr10:70672539-70762441 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    51
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    47
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Adamts14
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031948 VEGA Gene Model | MGI Sequence Detail 76327 C57BL/6J ±  kb
transcript OTTMUST00000079265 VEGA | MGI Sequence Detail 3645 Not Applicable  
polypeptide OTTMUSP00000042260 VEGA | MGI Sequence Detail 1209 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    395 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 16
    Primer pair 1
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 12
  • Earliest
    J:74679 Colige A, et al., Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3. J Biol Chem. 2002 Feb 22;277(8):5756-66
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory