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Adamts14 Gene Detail
Summary
  • Symbol
    Adamts14
  • Name
    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14
  • Synonyms
    Adamts-14, TS14
  • Feature Type
    protein coding gene
  • IDs
    MGI:2179942
    NCBI Gene: 237360
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:61197112-61273438 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 32.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    395 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2179942
protein coding gene Chr10:61197112-61273438 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017276
protein coding gene Chr10:60510413-60595824 (-)
A/J MGP_AJ_G0017254
protein coding gene Chr10:58711010-58787842 (-)
AKR/J MGP_AKRJ_G0017214
protein coding gene Chr10:60243470-60321923 (-)
BALB/cJ MGP_BALBcJ_G0017214
protein coding gene Chr10:58784767-58863534 (-)
C3H/HeJ MGP_C3HHeJ_G0017037
protein coding gene Chr10:60143673-60224986 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017672
protein coding gene Chr10:62647294-62744852 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015363
protein coding gene Chr10:55689268-55768955 (-)
CAST/EiJ MGP_CASTEiJ_G0016608
protein coding gene Chr10:60126369-60208235 (-)
CBA/J MGP_CBAJ_G0017009
protein coding gene Chr10:64984712-65091903 (-)
DBA/2J MGP_DBA2J_G0017114
protein coding gene Chr10:57983803-58061823 (-)
FVB/NJ MGP_FVBNJ_G0017108
protein coding gene Chr10:57239763-57317642 (-)
LP/J MGP_LPJ_G0017189
protein coding gene Chr10:60911970-61000056 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017136
protein coding gene Chr10:67348885-67438152 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017710
protein coding gene Chr10:60051720-60137397 (-)
PWK/PhJ MGP_PWKPhJ_G0016391
protein coding gene Chr10:57812314-57892779 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016174
protein coding gene Chr10:59401566-59480224 (-)
WSB/EiJ MGP_WSBEiJ_G0016672
protein coding gene Chr10:59976116-60060636 (-)



Homology
more
  • Human Ortholog
    ADAMTS14, ADAM metallopeptidase with thrombospondin type 1 motif 14
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ADAMTS14, ADAM metallopeptidase with thrombospondin type 1 motif 14
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 140766
    neXtProt AC: NX_Q8WXS8
    UniProt: Q8WXS8

  • Chr Location
    10q22.1; chr10:70672518-70762441 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 237360 NCBI Gene Model | MGI Sequence Detail 76327 C57BL/6J ±  kb
transcript NM_001081127 RefSeq | MGI Sequence Detail 5169 C57BL/6  
polypeptide NP_001074596 RefSeq | MGI Sequence Detail 1206 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR010294 ADAM-TS Spacer 1
    IPR024079 Metallopeptidase, catalytic domain superfamily
    IPR001590 Peptidase M12B, ADAM/reprolysin
    IPR002870 Peptidase M12B, propeptide
    IPR000884 Thrombospondin type-1 (TSP1) repeat
    IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Molecular
Reagents
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  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory