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Ts(1716)65Dn Cytogenetic Marker Detail
Summary
  • Symbol
    Ts(1716)65Dn
  • Name
    trisomy, Chr 16 translocation to Chr 17, Davisson 65
  • Synonyms
    trisomy 16, Ts65Dn
  • Feature Type
    chromosomal translocation
  • IDs
    MGI:2178111
Location & Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 16, Syntenic
  • Mapping Data
    1 experiment
Human Diseases
more
  • Diseases
    1 with Ts(17<16>)65Dn mouse models

Human Disease Mouse Models
      
IDs
View 4 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    5 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    59 phenotypes from 1 allele in 9 genetic backgrounds
    5 phenotypes from multigenic genotypes
    1 images
    243 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
References
more
  • Summaries
    All 245
    Diseases 5
    Phenotypes 243
  • Earliest
    J:30229 Davisson MT, et al., Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-33
  • Latest
    J:260938 Kleschevnikov AM, et al., Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome. Neurobiol Dis. 2017 Jul;103(None):1-10

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory