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Slc26a6
Gene Detail
 Symbol
Name
ID
Slc26a6
solute carrier family 26, member 6
MGI:2159728
Synonyms B930010B04Rik, CFEX, Pat1
Feature Type protein coding gene
Genetic Map
Chromosome 9
59.63 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:108854037-108912558 bp, + strand
From Ensembl annotation of GRCm38

  58522 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:99903  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 3 zebrafish

Protein SuperFamily: sulfate transport protein
Gene Tree: Slc26a6

Human
homologs
Human Homolog SLC26A6, solute carrier family 26 (anion exchanger), member 6
NCBI Gene ID 65010
neXtProt AC  NX_Q9BXS9
Human Chr (Location)  3p21.3; chr3:48625723-48635493 (-)  GRCh38
Alleles
and
phenotypes
All alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display abnormal proximal tubule and duodenal anion exchange, but are otherwise normal.
 
Gene Ontology
(GO)
classifications
All GO classifications: (85 annotations)
Process angiotensin-activated signaling pathway, anion transport, ...
Component apical plasma membrane, basolateral plasma membrane, ...
Function anion:anion antiporter activity, antiporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)    Images (1)
Theiler Stages: 23
Assay TypeResults
RNA in situ 1
cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000023259 (Evidence)
Entrez Gene171429 (Evidence)
DFCITC1584490, TC1604076, TC1615082, TC1633732, TC1698437, TC1698996
DoTSDT.101371240, DT.101371241, DT.101725964, DT.101725965, DT.101725966, DT.50314998, DT.91404229
NIA Mouse Gene IndexU011041
International Mouse Knockout Project StatusSlc26a6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023259 Ensembl Gene Model | MGI Sequence Detail 58522 C57BL/6J ±  kb
transcript ENSMUST00000098376 Ensembl | MGI Sequence Detail 2402 Not Applicable 
polypeptide ENSMUSP00000095979 Ensembl | MGI Sequence Detail 735 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(18 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002645 STAS domain
InterPro IPR001902 Sulphate anion transporter
InterPro IPR018045 Sulphate anion transporter, conserved site
InterPro IPR011547 Sulphate transporter
Protein Ontology PR:000015041 solute carrier family 26 member 6
References (Earliest) J:75064 Knauf F, et al., Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9425-30
(Latest) J:204021 Whittamore JM, et al., Sulfate secretion and chloride absorption are mediated by the anion exchanger DRA (Slc26a3) in the mouse cecum. Am J Physiol Gastrointest Liver Physiol. 2013 Jul 15;305(2):G172-84
All references(54)
Other
accession IDs
MGI:2443071

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/01/2014
MGI 5.18
The Jackson Laboratory