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Slc26a6
Gene Detail
Symbol

Name
ID
Slc26a6
solute carrier family 26, member 6
MGI:2159728
Synonyms
B930010B04Rik, CFEX, Pat1
Feature Type
protein coding gene
Genetic Map
Chromosome 9
59.63 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:108854697-108913049 bp, + strand
From VEGA annotation of GRCm38

  58353 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:99903  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 3 zebrafish

Protein SuperFamily: sulfate transport protein
Gene Tree: Slc26a6

Human
homologs
Human Homolog SLC26A6, solute carrier family 26 (anion exchanger), member 6
NCBI Gene ID 65010
neXtProt AC  NX_Q9BXS9
Human Chr (Location)  3p21.3; chr3:48625723-48635493 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display abnormal proximal tubule and duodenal anion exchange, but are otherwise normal.
 
Interactions
Slc26a6 interacts with 6 markers (Mir188, Mir320, Mir345, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (86 annotations)
Process angiotensin-activated signaling pathway, anion transport, ...
Component apical plasma membrane, basolateral plasma membrane, ...
Function anion:anion antiporter activity, antiporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000047370 (Evidence)
Ensembl Gene ModelENSMUSG00000023259 (Evidence)
Entrez Gene171429 (Evidence)
DFCITC1615082, TC1604076, TC1584490, TC1698996, TC1698437, TC1633732
DoTSDT.101725964, DT.101371240, DT.101371241, DT.101725965, DT.50314998, DT.91404229, DT.101725966
NIA Mouse Gene IndexU011041
International Mouse Knockout Project StatusSlc26a6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000047370 VEGA Gene Model | MGI Sequence Detail 58353 C57BL/6J ±  kb
transcript OTTMUST00000122394 VEGA | MGI Sequence Detail 2071 Not Applicable 
polypeptide OTTMUSP00000067156 VEGA | MGI Sequence Detail 629 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(16 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002645 STAS domain
InterPro IPR001902 Sulphate anion transporter
InterPro IPR018045 Sulphate anion transporter, conserved site
InterPro IPR011547 Sulphate transporter
Protein Ontology PR:000015041 solute carrier family 26 member 6
References
(Earliest) J:75064 Knauf F, et al., Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9425-30
(Latest) J:204021 Whittamore JM, et al., Sulfate secretion and chloride absorption are mediated by the anion exchanger DRA (Slc26a3) in the mouse cecum. Am J Physiol Gastrointest Liver Physiol. 2013 Jul 15;305(2):G172-84
All references(52)
Other
accession IDs
MGI:2443071

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory