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Kcnh7
Gene Detail
 Symbol
Name
ID
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
MGI:2159566
Synonyms 9330137I11Rik, erg3, Kv11.3
Feature Type protein coding gene
Genetic Map
Chromosome 2
36.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:62693414-63184287 bp, - strand
From VEGA annotation of GRCm38

  490874 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13249  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: potassium voltage-gated channel, subfamily H
Gene Tree: Kcnh7

Human
homologs
Human Homolog KCNH7, potassium voltage-gated channel, subfamily H (eag-related), member 7
NCBI Gene ID 90134
neXtProt AC  NX_Q9NS40
Human Synonyms  ERG3, HERG3, Kv11.3
Human Chr (Location)  2q24.2; chr2:162371407-162838747 (-)  GRCh38
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function inward rectifier potassium channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (86)    Tissues (51)    Images (18)
Theiler Stages: 11, 13, 15, 19, 21, 28
Assay TypeResults
RNA in situ 64
RNase protection 22
cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(7) cDNA(6) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000012800 (Evidence)
Ensembl Gene ModelENSMUSG00000059742 (Evidence)
Entrez Gene170738 (Evidence)
UniGene242532
DFCITC1593604, TC1594590, TC1596551, TC1596556
DoTSDT.101711137, DT.101712738, DT.91293112, DT.91330101
Consensus CDS ProjectCCDS38128.1
International Mouse Knockout Project StatusKcnh7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012800 VEGA Gene Model | MGI Sequence Detail 490874 C57BL/6J ±  kb
transcript OTTMUST00000030676 VEGA | MGI Sequence Detail 13321 Not Applicable 
polypeptide OTTMUSP00000013759 VEGA | MGI Sequence Detail 1195 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(13) UniProt(3)
Polymorphisms SNPs within 2kb(2996 from dbSNP Build 137)    SNPs within 2kb including multiple locations(3002)
Protein-related
information
ResourceIDDescription
InterPro IPR000595 Cyclic nucleotide-binding domain
InterPro IPR018490 Cyclic nucleotide-binding-like
InterPro IPR005821 Ion transport domain
InterPro IPR001610 PAC motif
InterPro IPR000014 PAS domain
InterPro IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG
InterPro IPR003967 Potassium channel, voltage-dependent, ERG
InterPro IPR014710 RmlC-like jelly roll fold
Protein Ontology PR:000000796 voltage-gated potassium channel KCNH7
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:193641 Nakano Y, et al., A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966
All references(28)
Other
accession IDs
MGI:2444334

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory