Kcnh7
Gene Detail

Symbol Name ID

Kcnh7 potassium voltage-gated channel, subfamily H (eag-related), member 7 MGI:2159566

Synonyms

9330137I11Rik, erg3, Kv11.3

Feature Type

protein coding gene

Genetic Map

Chromosome 2

36.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr2:62693414-63184287 bp, - strand From VEGA annotation of GRCm38   490874 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:13249  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: potassium voltage-gated channel, subfamily H
Gene Tree: Kcnh7

Human homologs

Human Homolog		KCNH7, potassium voltage-gated channel, subfamily H (eag-related), member 7
NCBI Gene ID		90134
neXtProt AC		NX_Q9NS40
Human Synonyms		ERG3, HERG3, Kv11.3
Human Chr (Location)		2q24.2; chr2:163227917-163695257 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (21 annotations)

Process	ion transmembrane transport, ion transport, ...
Component	integral to membrane, membrane
Function	inward rectifier potassium channel activity, ion channel activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (86)    Tissues (51)    Images (18)
Theiler Stages: 11, 13, 15, 19, 21, 28

Assay Type	Results
RNA in situ	64
RNase protection	22

cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) cDNA(6) Other(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000012800 (Evidence)
Ensembl Gene Model	ENSMUSG00000059742 (Evidence)
Entrez Gene	170738 (Evidence)
UniGene	242532
DFCI	TC1593604, TC1594590, TC1596551, TC1596556
DoTS	DT.101711137, DT.101712738, DT.91293112, DT.91330101
Consensus CDS Project	CCDS38128.1
International Mouse Knockout Project Status	Kcnh7

Sequences

Length	Strain/Species
genomic	OTTMUSG00000012800	VEGA Gene Model | MGI Sequence Detail	490874	C57BL/6J
transcript	OTTMUST00000030676	VEGA | MGI Sequence Detail	13321	Not Applicable
polypeptide	OTTMUSP00000013759	VEGA | MGI Sequence Detail	1195	Not Applicable

All sequences(35) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(2469 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000595	Cyclic nucleotide-binding domain
InterPro	IPR018490	Cyclic nucleotide-binding-like
InterPro	IPR005821	Ion transport domain
InterPro	IPR001610	PAC motif
InterPro	IPR000014	PAS domain
InterPro	IPR003938	Potassium channel, voltage-dependent, EAG/ELK/ERG
InterPro	IPR003967	Potassium channel, voltage-dependent, ERG
InterPro	IPR014710	RmlC-like jelly roll fold
Protein Ontology	PR:000000796	voltage-gated potassium channel KCNH7

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:193641 Nakano Y, et al., A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966
All references(27)

Other accession IDs

MGI:2444334