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Hamp2 Gene Detail
Summary
  • Symbol
    Hamp2
  • Name
    hepcidin antimicrobial peptide 2
  • Synonyms
    1810073K19Rik, HEPC2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153530
    NCBI Gene: 66438
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30922372-30924181 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 19.27 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153530
protein coding gene Chr7:30922372-30924681 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032051
protein coding gene Chr7:29961380-29964025 (-)
A/J MGP_AJ_G0032028
protein coding gene Chr7:29160457-29162209 (-)
AKR/J MGP_AKRJ_G0031961
protein coding gene Chr7:29882964-29884936 (-)
BALB/cJ MGP_BALBcJ_G0032035
protein coding gene Chr7:29321160-29322908 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0032501
protein coding gene Chr7:30960752-30990756 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029551
protein coding gene Chr7:30143664-30145338 (-)
CAST/EiJ MGP_CASTEiJ_G0031088
protein coding gene Chr7:23629393-23633020 (+)
CBA/J MGP_CBAJ_G0031721
protein coding gene Chr7:32422046-32424260 (-)
DBA/2J MGP_DBA2J_G0031872
protein coding gene Chr7:28900066-28901837 (-)
FVB/NJ MGP_FVBNJ_G0031829
protein coding gene Chr7:29016138-29018403 (-)
LP/J MGP_LPJ_G0031953
protein coding gene Chr7:30302619-30304720 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031865
protein coding gene Chr7:31647658-31649395 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0030648
protein coding gene Chr7:20407246-20409810 (-)
WSB/EiJ MGP_WSBEiJ_G0031198
protein coding gene Chr7:29794341-29818449 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66438 NCBI Gene Model | MGI Sequence Detail 1810 C57BL/6J ±  kb
    transcript NM_183257 RefSeq | MGI Sequence Detail 437 C57BL/6  
    polypeptide Q80T19 UniProt | EBI | MGI Sequence Detail 83 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      Genomic 1
      cDNA 6
      Primer pair 2
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1913688
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 5
      Gene Ontology 3
      Phenotypes 3
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:292039 Lefebvre T, et al., Genetic background influences hepcidin response to iron imbalance in a mouse model of hemolytic anemia (Congenital erythropoietic porphyria). Biochem Biophys Res Commun. 2019 Dec 3;520(2):297-303

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/10/2020
    MGI 6.16
    The Jackson Laboratory