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Hnmt
Gene Detail
 Symbol
Name
ID
Hnmt
histamine N-methyltransferase
MGI:2153181
Synonyms 1500031F01Rik
Feature Type protein coding gene
Genetic Map
Chromosome 2
16.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:24002910-24049394 bp, - strand
From VEGA annotation of GRCm38

  46485 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5032  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 2 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: histamine N-methyltransferase
Gene Tree: Hnmt

Human
homologs
Human Homolog HNMT, histamine N-methyltransferase
NCBI Gene ID 3176
neXtProt AC  NX_P50135
Human Synonyms  HMT, HNMT-S1, HNMT-S2
Human Chr (Location)  2q22.1; chr2:137964238-138016364 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human HNMT
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process methylation, regulation of neurotransmitter levels
Component cytoplasm, extracellular vesicular exosome, ...
Function histamine N-methyltransferase activity, methyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(21)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(22) cDNA(22)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000011800 (Evidence)
Ensembl Gene ModelENSMUSG00000026986 (Evidence)
Entrez Gene140483 (Evidence)
UniGene33120
DFCITC1581113
DoTSDT.101140822, DT.101366246, DT.489407
NIA Mouse Gene IndexU022362
EC2.1.1.8
Consensus CDS ProjectCCDS15731.1
International Mouse Knockout Project StatusHnmt
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011800 VEGA Gene Model | MGI Sequence Detail 46485 C57BL/6J ±  kb
transcript OTTMUST00000027697 VEGA | MGI Sequence Detail 1656 Not Applicable 
polypeptide OTTMUSP00000012588 VEGA | MGI Sequence Detail 295 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(6) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(110 from dbSNP Build 137)    SNPs within 2kb including multiple locations(112)
Protein-related
information
ResourceIDDescription
InterPro IPR016673 Histamine N-methyltransferase
Protein Ontology PR:000008656 histamine N-methyltransferase
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)
Other
accession IDs
MGI:1923597, MGI:2139051

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory