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Slc2a9
Gene Detail
 Symbol
Name
ID
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
MGI:2152844
Synonyms Glut9, SLC2a9A, SLC2A9B
Feature Type protein coding gene
Genetic Map
Chromosome 5
20.43 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:38349273-38503143 bp, - strand
From VEGA annotation of GRCm38

  153871 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69290  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Gene Tree: Slc2a9

Human
homologs
Human Homolog SLC2A9, solute carrier family 2 (facilitated glucose transporter), member 9
NCBI Gene ID 56606
neXtProt AC  NX_Q9NRM0
Human Synonyms  GLUT9, GLUTX, UAQTL2, URATv1
Human Chr (Location)  4p16.1; chr4:9779807-10040248 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SLC2A9
Alleles
and
phenotypes
All alleles(7) : Gene trapped(2) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele show partial prenatal lethality, polydipsia, hyperuricemia, hyperuricosuria and polyuria, and develop urate nephropathy, characterized by obstructive lithiasis, tubulointerstitial inflammation, cortical fibrosis, renal insufficiency and reduced male weight.
 
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process carbohydrate transport, glucose transport, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function glucose transmembrane transporter activity
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (53)    Tissues (37)    Images (6)
Theiler Stages: 1, 2, 4, 10, 23, 26, 28
Assay TypeResults
Immunohistochemistry 4
RNA in situ 25
Northern blot 8
Western blot 9
RT-PCR 7
cDNA source data(26)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(31) cDNA(27) Primer pair(4)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000026252 (Evidence)
Ensembl Gene ModelENSMUSG00000005107 (Evidence)
Entrez Gene117591 (Evidence)
UniGene260137
DFCITC1583515, TC1586383
DoTSDT.101202595, DT.102536798, DT.40155645, DT.40158026, DT.94333527
NIA Mouse Gene IndexU026138
Consensus CDS ProjectCCDS19256.1, CCDS51482.1, CCDS51483.1, CCDS51484.1
International Mouse Knockout Project StatusSlc2a9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026252 VEGA Gene Model | MGI Sequence Detail 153871 C57BL/6J ±  kb
transcript OTTMUST00000064925 VEGA | MGI Sequence Detail 3602 Not Applicable 
polypeptide OTTMUSP00000032287 VEGA | MGI Sequence Detail 538 Not Applicable 

For the selected sequences
All sequences(88) RefSeq(18) UniProt(10)
Polymorphisms SNPs within 2kb(1172 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005828 General substrate transporter
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR016196 Major facilitator superfamily domain, general substrate transporter
InterPro IPR003663 Sugar/inositol transporter
InterPro IPR005829 Sugar transporter, conserved site
Protein Ontology PR:000015072 solute carrier family 2, facilitated glucose transporter member 9
References (Earliest) J:72229 Hurle B, et al., Physical Mapping of the Mouse Tilted Locus Identifies an Association between Human Deafness Loci DFNA6/14 and Vestibular System Development. Genomics. 2001 Oct;77(3):189-99
(Latest) J:200937 Preitner F, et al., Urate-induced acute renal failure and chronic inflammation in liver-specific Glut9 knockout mice. Am J Physiol Renal Physiol. 2013 Sep;305(5):F786-95
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory