About   Help   FAQ
Slc2a9 Gene Detail
Summary
  • Symbol
    Slc2a9
  • Name
    solute carrier family 2 (facilitated glucose transporter), member 9
  • Synonyms
    Glut9, SLC2a9A, SLC2A9B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2152844
    NCBI Gene: 117591
  • Gene Overview
    MyGene.info: SLC2A9
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr5:38349273-38503143 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      153871 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 20.43 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SLC2A9, solute carrier family 2 member 9
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SLC2A9, solute carrier family 2 member 9
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GLUT9, GLUTX, UAQTL2, URATv1
  • Links
    NCBI Gene ID: 56606
    neXtProt AC: NX_Q9NRM0
    UniProt: Q9NRM0

  • Chr Location
    4p16.1; chr4:9771125-10040248 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    49 phenotypes from 3 alleles in 4 genetic backgrounds
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele show partial prenatal lethality, polydipsia, hyperuricemia, hyperuricosuria and polyuria, and develop urate nephropathy, characterized by obstructive lithiasis, tubulointerstitial inflammation, cortical fibrosis, renal insufficiency and reduced male weight.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000026252 VEGA Gene Model | MGI Sequence Detail 153871 C57BL/6J ±  kb
    transcript OTTMUST00000064925 VEGA | MGI Sequence Detail 3602 Not Applicable  
    polypeptide OTTMUSP00000032287 VEGA | MGI Sequence Detail 538 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      1166 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      11 Sequences
    • InterPro Domains
      IPR005828 Major facilitator, sugar transporter-like
      IPR020846 Major facilitator superfamily domain
      IPR036259 MFS transporter superfamily
      IPR003663 Sugar/inositol transporter
      IPR005829 Sugar transporter, conserved site
    Molecular
    Reagents
    less
    • All nucleic 31
      cDNA 27
      Primer pair 4

      Microarray probesets 2
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 2
      Phenotypes 26
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:221544 DeBosch BJ, et al., Early-onset metabolic syndrome in mice lacking the intestinal uric acid transporter SLC2A9. Nat Commun. 2014;5:4642

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    06/05/2018
    MGI 6.12
    The Jackson Laboratory