Slc2a9
Gene Detail

Symbol Name ID

Slc2a9 solute carrier family 2 (facilitated glucose transporter), member 9 MGI:2152844

Synonyms

Glut9, SLC2a9A, SLC2A9B

Feature Type

protein coding gene

Genetic Map

Chromosome 5

20.43 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr5:38349273-38503143 bp, - strand From VEGA annotation of GRCm38   153871 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:69290  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Gene Tree: Slc2a9

Human homologs

Human Homolog		SLC2A9, solute carrier family 2 (facilitated glucose transporter), member 9
NCBI Gene ID		56606
neXtProt AC		NX_Q9NRM0
Human Synonyms		GLUT9, GLUTX, UAQTL2, URATv1
Human Chr (Location)		4p16.1; chr4:9827848-10041872 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SLC2A9

Alleles and phenotypes

All alleles(7) : Targeted(5) Gene trapped(2)
 

Mice homozygous for a knock-out allele show partial prenatal lethality, polydipsia, hyperuricemia, hyperuricosuria and polyuria, and develop urate nephropathy, characterized by obstructive lithiasis, tubulointerstitial inflammation, cortical fibrosis, renal insufficiency and reduced male weight.

 

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	carbohydrate transport, glucose transport, ...
Component	integral to membrane, integral to plasma membrane, ...
Function	glucose transmembrane transporter activity

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (32)    Tissues (17)    Images (4)
Theiler Stages: 1, 2, 4, 10, 23, 28

Assay Type	Results
Immunohistochemistry	4
RNA in situ	4
Northern blot	8
Western blot	9
RT-PCR	7

cDNA source data(26)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(31) cDNA(27) Primer pair(4)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000026252 (Evidence)
Ensembl Gene Model	ENSMUSG00000005107 (Evidence)
Entrez Gene	117591 (Evidence)
UniGene	260137
DFCI	TC1583515, TC1586383
DoTS	DT.101202595, DT.102536798, DT.40155645, DT.40158026, DT.94333527
NIA Mouse Gene Index	U026138
Consensus CDS Project	CCDS19256.1, CCDS51482.1, CCDS51483.1, CCDS51484.1
International Mouse Knockout Project Status	Slc2a9

Sequences

Length	Strain/Species
genomic	OTTMUSG00000026252	VEGA Gene Model | MGI Sequence Detail	153871	C57BL/6J
transcript	OTTMUST00000064925	VEGA | MGI Sequence Detail	3602	Not Applicable
polypeptide	OTTMUSP00000032287	VEGA | MGI Sequence Detail	538	Not Applicable

All sequences(78) RefSeq(8) UniProt(10)

Polymorphisms

SNPs(750 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR005828	General substrate transporter
InterPro	IPR020846	Major facilitator superfamily domain
InterPro	IPR016196	Major facilitator superfamily domain, general substrate transporter
InterPro	IPR003663	Sugar/inositol transporter
InterPro	IPR005829	Sugar transporter, conserved site
Protein Ontology	PR:000015072	solute carrier family 2, facilitated glucose transporter member 9

References

(Earliest) J:72229 Hurle B, et al., Physical Mapping of the Mouse Tilted Locus Identifies an Association between Human Deafness Loci DFNA6/14 and Vestibular System Development. Genomics. 2001 Oct;77(3):189-99
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)