Pip4k2c
Gene Detail

Symbol Name ID

Pip4k2c phosphatidylinositol-5-phosphate 4-kinase, type II, gamma MGI:2152214

Synonyms

Pip5k2c

Feature Type

protein coding gene

Genetic Map

Chromosome 10

74.50 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr10:127197067-127211622 bp, - strand From NCBI annotation of GRCm38   14556 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:23484  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Protein SuperFamily: phosphatidylinositol-4-phosphate 5-kinase type II alpha
Gene Tree: Pip4k2c

Human homologs

Human Homolog		PIP4K2C, phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
NCBI Gene ID		79837
neXtProt AC		NX_Q8TBX8
Human Synonyms		PIP5K2C
Human Chr (Location)		12q13.3; chr12:57984942-57997211 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	phosphatidylinositol metabolic process, phosphorylation
Component	cytoplasm, endoplasmic reticulum, ...
Function	1-phosphatidylinositol-4-phosphate 5-kinase activity, 1-phosphatidylinositol-5-phosphate 4-kinase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (179)    Tissues (137)    Images (10)
Theiler Stages: 22, 26, 28

Assay Type	Results
RNA in situ	178
Northern blot	1

cDNA source data(123)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(126) cDNA(124) Primer pair(1) Other(1)
Microarray probesets(5)

Other database links

Ensembl Gene Model	ENSMUSG00000025417 (Evidence)
Entrez Gene	117150 (Evidence)
UniGene	22682
DFCI	TC1572449, TC1713722, TC1756825
DoTS	DT.101280560, DT.533438
NIA Mouse Gene Index	U032329
EC	2.7.1.149
Consensus CDS Project	CCDS24232.1
International Mouse Knockout Project Status	Pip4k2c

Sequences

Length	Strain/Species
genomic	117150	NCBI Gene Model | MGI Sequence Detail	14556	C57BL/6J
transcript	NM_054097	RefSeq | MGI Sequence Detail	3374	C57BL/6
polypeptide	Q91XU3	UniProt | EBI | MGI Sequence Detail	421	Not Applicable

All sequences(38) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(92 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023610	Phosphatidylinositol-4-phosphate 5-kinase
InterPro	IPR002498	Phosphatidylinositol-4-phosphate 5-kinase, core
InterPro	IPR016034	Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
Protein Ontology	PR:000012743	phosphatidylinositol-5-phosphate 4-kinase type-2 gamma

Graphical View of Protein Domain Structure

References

(Earliest) J:75718 Akiba Y, et al., Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development. Brain Res Gene Expr Patterns. 2002 Jan;1(2):123-33
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)