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Pip4k2c
Gene Detail
 Symbol
Name
ID
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
MGI:2152214
Synonyms Pip5k2c
Feature Type protein coding gene
Genetic Map
Chromosome 10
74.50 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:127197067-127211622 bp, - strand
From NCBI annotation of GRCm38

  14556 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23484  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Protein SuperFamily: phosphatidylinositol-4-phosphate 5-kinase type II alpha
Gene Tree: Pip4k2c

Human
homologs
Human Homolog PIP4K2C, phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
NCBI Gene ID 79837
neXtProt AC  NX_Q8TBX8
Human Synonyms  PIP5K2C
Human Chr (Location)  12q13.3; chr12:57591159-57603428 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pip4k2c interacts with 254 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process phosphatidylinositol metabolic process, phosphatidylinositol phosphorylation, ...
Component cytoplasm, endoplasmic reticulum, ...
Function 1-phosphatidylinositol-4-phosphate 5-kinase activity, 1-phosphatidylinositol-5-phosphate 4-kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (179)    Tissues (137)    Images (10)
Theiler Stages: 22, 26, 28
Assay TypeResults
RNA in situ 178
Northern blot 1
cDNA source data(125)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(128) cDNA(126) Primer pair(1) Other(1)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000025417 (Evidence)
Entrez Gene117150 (Evidence)
UniGene22682
DFCITC1572449, TC1713722, TC1756825
DoTSDT.101280560, DT.533438
NIA Mouse Gene IndexU032329
EC2.7.1.149
Consensus CDS ProjectCCDS24232.1
International Mouse Knockout Project StatusPip4k2c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 117150 NCBI Gene Model | MGI Sequence Detail 14556 C57BL/6J ±  kb
transcript NM_054097 RefSeq | MGI Sequence Detail 3374 C57BL/6 
polypeptide Q91XU3 UniProt | EBI | MGI Sequence Detail 421 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(100 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023610 Phosphatidylinositol-4-phosphate 5-kinase
InterPro IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
InterPro IPR016034 Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
InterPro IPR027483 Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
InterPro IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain
Protein Ontology PR:000012743 phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Graphical View of Protein Domain Structure
References (Earliest) J:75718 Akiba Y, et al., Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development. Brain Res Gene Expr Patterns. 2002 Jan;1(2):123-33
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory