Pip4k2c Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
MGI:2152214

32 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pip4k2c^{tm1b(KOMP)Wtsi}/Pip4k2c^{tm1b(KOMP)Wtsi} C57BL/6N-Pip4k2c^{tm1b(KOMP)Wtsi}/J	abnormal auditory brainstem response	J:211773
	hyperactivity	J:211773
	increased fasting circulating glucose level	J:211773
Pip4k2c^{tm1b(KOMP)Wtsi}/Pip4k2c^{tm1b(KOMP)Wtsi} involves: C57BL/6J * C57BL/6N	abnormal circulating chemokine level	J:234283
	abnormal circulating protein level	J:234283
	abnormal T cell activation	J:234283
	chronic inflammation	J:234283
	chronic liver inflammation	J:234283
	decreased blood urea nitrogen level	J:234283
	decreased regulatory T cell number	J:234283
	normal growth/size/body region phenotype	J:234283
	normal homeostasis/metabolism phenotype	J:234283
	increased CD4-positive, alpha-beta T cell number	J:234283
	increased CD8-positive, alpha-beta T cell number	J:234283
	increased circulating aspartate transaminase level	J:234283
	increased circulating interferon-gamma level	J:234283
	increased circulating interleukin-2 level	J:234283
	increased circulating interleukin-4 level	J:234283
	increased circulating interleukin-10 level	J:234283
	increased circulating interleukin-12 level	J:234283
	increased circulating interleukin-12b level	J:234283
	increased IgG3 level	J:234283
	increased inflammatory response	J:234283
	increased interferon-gamma secretion	J:234283
	increased interleukin-17 secretion	J:234283
	increased T cell proliferation	J:234283
	increased T-helper cell number	J:234283
	intestinal inflammation	J:234283
	kidney inflammation	J:234283
	lung inflammation	J:234283
	pale liver	J:234283
	salivary gland inflammation	J:234283

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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