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Baz2a Gene Detail
Summary
  • Symbol
    Baz2a
  • Name
    bromodomain adjacent to zinc finger domain, 2A
  • Synonyms
    C030005G16Rik, mKIAA0314, Tip5, Walp3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151152
    NCBI Gene: 116848
  • Alliance
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:127927453-127965172 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 76.40 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    220 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2151152
protein coding gene Chr10:127927446-127965172 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017848
protein coding gene Chr10:131769387-131808145 (+)
A/J MGP_AJ_G0017823
protein coding gene Chr10:126496281-126537210 (+)
AKR/J MGP_AKRJ_G0017786
protein coding gene Chr10:130227460-130264176 (+)
BALB/cJ MGP_BALBcJ_G0017787
protein coding gene Chr10:126881077-126920688 (+)
C3H/HeJ MGP_C3HHeJ_G0017610
protein coding gene Chr10:130381584-130418476 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018242
protein coding gene Chr10:136253664-136296239 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015920
protein coding gene Chr10:120458927-120492133 (+)
CAST/EiJ MGP_CASTEiJ_G0017171
protein coding gene Chr10:131082919-131124665 (+)
CBA/J MGP_CBAJ_G0017580
protein coding gene Chr10:141779496-141822360 (+)
DBA/2J MGP_DBA2J_G0017686
protein coding gene Chr10:125570715-125611321 (+)
FVB/NJ MGP_FVBNJ_G0017681
protein coding gene Chr10:124503167-124541485 (+)
LP/J MGP_LPJ_G0017760
protein coding gene Chr10:132384367-132422962 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017709
protein coding gene Chr10:144370716-144409623 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018282
protein coding gene Chr10:130311403-130349450 (+)
PWK/PhJ MGP_PWKPhJ_G0016956
protein coding gene Chr10:125820824-125858094 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016745
protein coding gene Chr10:129394674-129436767 (+)
WSB/EiJ MGP_WSBEiJ_G0017230
protein coding gene Chr10:130528110-130567531 (+)



Homology
more
  • Human Ortholog
    BAZ2A, bromodomain adjacent to zinc finger domain 2A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BAZ2A, bromodomain adjacent to zinc finger domain 2A
  • Synonyms
    TIP5, WALp3
  • Links
    NCBI Gene ID: 11176
    neXtProt AC: NX_Q9UIF9
    UniProt: Q9UIF9

  • Chr Location
    12q13.3; chr12:56595596-56636816 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 116848 NCBI Gene Model | MGI Sequence Detail 37720 C57BL/6J ±  kb
    transcript NM_054078 RefSeq | MGI Sequence Detail 8369 Not Specified  
    polypeptide Q91YE5 UniProt | EBI | MGI Sequence Detail 1889 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 207
      cDNA 205
      Primer pair 2

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1925788, MGI:2143475, MGI:2143919
    References
    more
    • Summaries
      All 62
      Developmental Gene Expression 12
      Gene Ontology 11
      Phenotypes 11
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:326413 Jia Y, et al., In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration. Cell Stem Cell. 2022 Mar 3;29(3):372-385.e8

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    08/09/2022
    MGI 6.21
    The Jackson Laboratory