Sequence Detail

ID/Version

Q91YE5 Q80U42 Q3U235 (UniProt | EBI)

Last sequence update: 2009-09-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Bromodomain adjacent to zinc finger domain protein 2A;AltName: Full=Transcription termination factor I-interacting protein 5; Short=TTF-I-interacting protein 5; Short=Tip5;

Provider

SWISS-PROT

Sequence

Polypeptide 1889 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Baz2a	bromodomain adjacent to zinc finger domain, 2A	31	114	3	85

Sequence references in MGI

J:71381 Strohner R, et al., NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines. EMBO J. 2001 Sep 3;20(17):4892-900
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100129 Zhou Y, et al., The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing. Curr Biol. 2005 Aug 9;15(15):1434-8
J:111312 Mayer C, et al., Intergenic transcripts regulate the epigenetic state of rRNA genes. Mol Cell. 2006 May 5;22(3):351-61
J:150911 Mayer C, et al., The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus. EMBO Rep. 2008 Aug;9(8):774-80
J:150926 Zhou Y, et al., The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription. EMBO J. 2002 Sep 2;21(17):4632-40
J:150958 Zhou Y, et al., Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing. Nat Cell Biol. 2009 Aug;11(8):1010-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89