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Cnnm2 Gene Detail
Summary
  • Symbol
    Cnnm2
  • Name
    cyclin M2
  • Synonyms
    Acdp2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151054
    NCBI Gene: 94219
  • Gene Overview
    MyGene.info: CNNM2
Location & Maps
more
  • Sequence Map
    Chr19:46761596-46878795 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      117200 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CNNM2, cyclin and CBS domain divalent metal cation transport mediator 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CNNM2, cyclin and CBS domain divalent metal cation transport mediator 2
    Orthology source: HomoloGene
  • Synonyms
    ACDP2, HOMG6, HOMGSMR
  • Links
    NCBI Gene ID: 54805
    neXtProt AC: NX_Q9H8M5

  • Chr Location
    10q24.32; chr10:102918293-103078587 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9761
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CNNM2
  • Gene Tree
Human Diseases
more
  • Diseases
    2 with human CNNM2 associations

Human Disease Mouse Models
       Hypomagnesemia 6, Renal; HOMG6   OMIM: 613882
Hypomagnesemia, Seizures, and Mental Retardation; HOMGSMR   OMIM: 616418
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    120
  • Gene trapped
    116
  • Targeted
    4
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064105 Ensembl Gene Model | MGI Sequence Detail 117200 C57BL/6J ±  kb
transcript ENSMUST00000099373 Ensembl | MGI Sequence Detail 3558 Not Applicable  
polypeptide ENSMUSP00000096972 Ensembl | MGI Sequence Detail 875 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    782 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 5
Other
Accession IDs
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MGI:2147641, MGI:2147691
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:215949 Hirata Y, et al., Mg2+-dependent interactions of ATP with the cystathionine-beta-synthase (CBS) domains of a magnesium transporter. J Biol Chem. 2014 May 23;289(21):14731-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory