Cnnm2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cnnm2
cyclin M2
MGI:2151054

24 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cnnm2^{tm1.1(KOMP)Vlcg}/Cnnm2⁺ C57BL/6N-Cnnm2^{tm1.1(KOMP)Vlcg}/Ucd	hemorrhage	J:211773
	increased bone mineral density	J:211773
	spina bifida	J:211773
Cnnm2^{tm1.1(KOMP)Vlcg}/Cnnm2^{tm1.1(KOMP)Vlcg} C57BL/6N-Cnnm2^{tm1.1(KOMP)Vlcg}/Ucd	abnormal head shape	J:211773
	abnormal head size	J:211773
	edema	J:211773
	embryonic growth retardation	J:211773
	exencephaly	J:211773
	hemorrhage	J:211773
	microcephaly	J:211773
	microphthalmia	J:211773
	preweaning lethality, complete penetrance	J:211773
	spina bifida	J:211773
Cnnm2^tm1.1Hmik/Cnnm2⁺ involves: C57BL * C57BL/6J * DBA	abnormal homeostasis	J:303151
	decreased circulating magnesium level	J:303151
	decreased systemic arterial diastolic blood pressure	J:303151
	decreased systemic arterial systolic blood pressure	J:303151
	normal mortality/aging	J:303151
Cnnm2^tm1.1Hmik/Cnnm2^tm1.1Hmik involves: C57BL * C57BL/6J * DBA	lethality throughout fetal growth and development, complete penetrance	J:303151
Cnnm2^tm1Hmik/Cnnm2^tm1Hmik Tg(Six2-EGFP/cre)1Amc/0 involves: C57BL/6J * CD-1	decreased circulating magnesium level	J:303151
	decreased systemic arterial diastolic blood pressure	J:303151
	decreased systemic arterial systolic blood pressure	J:303151
	normal growth/size/body region phenotype	J:303151
	normal mortality/aging	J:303151
Cnnm2^{Tn(pb-Act-RFP)1.090428026-HRAZhu}/Cnnm2^{Tn(pb-Act-RFP)1.090428026-HRAZhu} involves: FVB/NJ	abnormal brain development	J:378174
	abnormal cardiovascular development	J:378174
	abnormal liver development	J:378174
	abnormal vascular development	J:378174
	embryonic growth retardation	J:378174
	embryonic lethality during organogenesis, incomplete penetrance	J:378174
	lethality during fetal growth through weaning, complete penetrance	J:378174

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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