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Slc38a1
Gene Detail
Symbol

Name
ID
Slc38a1
solute carrier family 38, member 1
MGI:2145895
Synonyms
NAT2
Feature Type
protein coding gene
Genetic Map
Chromosome 15
52.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:96571418-96642913 bp, - strand
From NCBI annotation of GRCm38

  71496 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12745  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: SLC38A1
Gene Tree: Slc38a1

Human
homologs
SLC38A1, solute carrier family 38, member 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 81539
neXtProt AC: NX_Q9H2H9

Human Synonyms: ATA1, NAT2, SAT1, SNAT1

Human Chr (Location): 12q13.11; chr12:46183055-46269425 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(118) : Gene trapped(113) Radiation induced(1) Targeted(4)
Genomic Mutations involving Slc38a1 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Phenotype Images(2)
Interactions
Slc38a1 interacts with 408 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process amino acid transport, cation transmembrane transport, ...
Component axon, extracellular exosome, ...
Function L-glutamine transmembrane transporter activity, symporter activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (306)    Tissues (47)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 294
RT-PCR 12
cDNA source data(20)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc38a1    NEW 
Molecular
reagents
All nucleic(22) cDNA(20) Primer pair(2)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000023169 (Evidence)
Entrez Gene 105727 (Evidence)
DFCI TC1574138, TC1593730, TC1585244, TC1594305, TC1628778, TC1628022
DoTS DT.101241843, DT.490148, DT.101255694, DT.91333090, DT.91439206, DT.97407459, DT.97352970
NIA Mouse Gene Index U036596
Consensus CDS Project CCDS27777.1
International Mouse Phenotyping Consortium Status Slc38a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 105727 NCBI Gene Model | MGI Sequence Detail 71496 C57BL/6J ±  kb
transcript NM_134086 RefSeq | MGI Sequence Detail 7752 C57BL/6 
polypeptide Q8K2P7 UniProt | EBI | MGI Sequence Detail 485 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(8) UniProt(2)
Polymorphisms
SNPs within 2kb(664 from dbSNP Build 137)    SNPs within 2kb including multiple locations(678)
Protein-related
information
ResourceIDDescription
InterPro IPR013057 Amino acid transporter, transmembrane
Protein Ontology PR:000015118 sodium-coupled neutral amino acid transporter 1
Graphical View of Protein Domain Structure
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:176894 Audette MC, et al., Antenatal dexamethasone treatment in midgestation reduces system A-mediated transport in the late-gestation murine placenta. Endocrinology. 2011 Sep;152(9):3561-70
All references(42)
Other
accession IDs
MGI:2145903, MGI:2146107, MGI:2146126

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory