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Slc38a1 Gene Detail
Summary
  • Symbol
    Slc38a1
  • Name
    solute carrier family 38, member 1
  • Synonyms
    NAT2, SNAT1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145895
    NCBI Gene: 105727
  • Alliance
    genome feature page
  • Transcription Start Sites
    26 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:96469299-96540794 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 52.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2177 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145895
 protein coding gene Chr15:96469299-96541396 (-)
129S1/SvImJ ENSMUSG00200047514
 protein coding gene Chr15:93663507-93735638 (-)
A/J ENSMUSG00195043797
 protein coding gene Chr15:93517447-93589639 (-)
AKR/J ENSMUSG00220045392
 protein coding gene Chr15:93517192-93587367 (-)
BALB/cJ ENSMUSG00180041941
 protein coding gene Chr15:93441592-93513187 (-)
C3H/HeJ ENSMUSG00175034165
 protein coding gene Chr15:93697738-93769926 (-)
C57BL/6NJ ENSMUSG00215050575
 protein coding gene Chr15:93504490-93576082 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020206
 protein coding gene Chr15:90307483-90379255 (-)
CAST/EiJ ENSTCUG00005042422
 protein coding gene Chr15:92981532-93051725 (-)
CBA/J ENSMUSG00210026856
 protein coding gene Chr15:93477124-93547283 (-)
DBA/2J ENSMUSG00185037113
 protein coding gene Chr15:93527342-93597520 (-)
FVB/NJ ENSMUSG00205026712
 protein coding gene Chr15:93244760-93316355 (-)
JF1/MsJ ENSUMUG00000025449
 protein coding gene Chr15:93023954-93095416 (-)
LP/J ENSMUSG00230032205
 protein coding gene Chr15:96843143-96915277 (-)
NOD/ShiLtJ ENSMUSG00190046233
 protein coding gene Chr15:93535316-93607501 (-)
NZO/HlLtJ ENSMUSG00225041339
 protein coding gene Chr15:97143462-97215603 (-)
PWK/PhJ ENSLUMG00010049071
 protein coding gene Chr15:93180865-93253064 (-)
SPRET/EiJ ENSMSPG00010047891
 protein coding gene Chr15:95013832-95078282 (-)
WSB/EiJ ENSIUOG00005037111
 protein coding gene Chr15:93592199-93666798 (-)



Homology
more
  • Human Ortholog
    SLC38A1, solute carrier family 38 member 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC38A1, solute carrier family 38 member 1
  • Synonyms
    ATA1, NAT2, SAT1, SNAT1
  • Links
    NCBI Gene ID: 81539
    UniProt: Q9H2H9

  • Chr Location
    12q13.11; chr12:46183054-46270070 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SLC38A1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    38 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    60
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    976
  • Tissues
    84
  • cDNA Data
    24
  • Literature Summary
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023169 Ensembl Gene Model | MGI Sequence Detail 71496 C57BL/6J ±  kb
transcript ENSMUST00000100262 Ensembl | MGI Sequence Detail 3183 Not Applicable  
polypeptide ENSMUSP00000097833 Ensembl | MGI Sequence Detail 485 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 24
    Primer pair 3
    Antibodies 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145903, MGI:2146107, MGI:2146126
References
more
  • Summaries
    All 92
    Developmental Gene Expression 11
    Diseases 1
    Gene Ontology 12
    Phenotypes 38
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory