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Fbxw11 Gene Detail
Summary
  • Symbol
    Fbxw11
  • Name
    F-box and WD-40 domain protein 11
  • Synonyms
    2310065A07Rik, BTRC2, BTRCP2, Fbxw1b, HOS, mKIAA0696
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144023
    NCBI Gene: 103583
  • Gene Overview
    MyGene.info: FBXW11
Location & Maps
more
  • Sequence Map
    Chr11:32642724-32746789 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      104066 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 19.02 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    FBXW11, F-box and WD repeat domain containing 11
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FBXW11, F-box and WD repeat domain containing 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BTRC2, BTRCP2, Fbw11, FBW1B, FBXW1B, Hos
  • Links
    NCBI Gene ID: 23291
    neXtProt AC: NX_Q9UKB1

  • Chr Location
    5q35.1; chr5:171861549-172006873 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from multigenic genotypes
    14 phenotype references
  • All Mutations and Alleles
    66
  • Chemically induced (other)
    1
  • Gene trapped
    61
  • Targeted
    4
  • Genomic Mutations
    1 involving Fbxw11
  • Incidental Mutations
    Mutagenetix , APF , CvDC
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    24
  • Tissues
    15
  • cDNA Data
    16
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005386 VEGA Gene Model | MGI Sequence Detail 104066 C57BL/6J ±  kb
transcript OTTMUST00000012013 VEGA | MGI Sequence Detail 3938 Not Applicable  
polypeptide OTTMUSP00000005567 VEGA | MGI Sequence Detail 542 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    523 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 4
Other
Accession IDs
less
MGI:1919630
References
more
  • Summaries
    All 44
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228222 Nakagawa T, et al., S6 Kinase- and beta-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation. Mol Cell Biol. 2015 Oct;35(20):3517-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory