About   Help   FAQ
Cyp4v3 Gene Detail
Summary
  • Symbol
    Cyp4v3
  • Name
    cytochrome P450, family 4, subfamily v, polypeptide 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142763
    NCBI Gene: 102294
  • Gene Overview
    MyGene.info: CYP4V2
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr8:45304944-45333216 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      28273 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 25.17 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CYP4V2, cytochrome P450 family 4 subfamily V member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CYP4V2, cytochrome P450 family 4 subfamily V member 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BCD, CYP4AH1
  • Links
    NCBI Gene ID: 285440
    neXtProt AC: NX_Q6ZWL3
    UniProt: Q6ZWL3

  • Chr Location
    4q35.1-q35.2; chr4:186191520-186213463 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Cyp4v3 mouse models; 1 with human CYP4V2 associations

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null mice exhibit corneoretinal crystal accumulation and systemic dyslipidemia characteristic of Bietti Crystalline Dystrophy.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000026456 VEGA Gene Model | MGI Sequence Detail 28273 C57BL/6J ±  kb
    transcript OTTMUST00000065425 VEGA | MGI Sequence Detail 3808 Not Applicable  
    polypeptide OTTMUSP00000032611 VEGA | MGI Sequence Detail 525 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      271 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 45
      cDNA 44
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2142718
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 3
      Phenotypes 5
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:230232 Lockhart CM, et al., Generation and characterization of a murine model of Bietti crystalline dystrophy. Invest Ophthalmol Vis Sci. 2014 Sep;55(9):5572-81

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    09/11/2018
    MGI 6.12
    The Jackson Laboratory