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Slc35d1 Gene Detail
Summary
  • Symbol
    Slc35d1
  • Name
    solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
  • Synonyms
    UGTREL7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140361
    NCBI Gene: 242585
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr4:103170649-103215164 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      44516 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 47.43 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SLC35D1, solute carrier family 35 member D1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC35D1, solute carrier family 35 member D1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SHNKND, UGTREL7
  • Links
    NCBI Gene ID: 23169
    neXtProt AC: NX_Q9NTN3
    UniProt: Q9NTN3

  • Chr Location
    1p31.3; chr1:66999332-67054397 (-)  GRCh38.p7
Human Diseases
more
  • Diseases
    1 with Slc35d1 mouse models; 1 with human SLC35D1 associations

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit neonatal lethality and chondrodystrophy associated with impaired chondroitin sulfate biosynthesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
    1
  • Tissues
    1
  • cDNA Data
    47
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000008067 VEGA Gene Model | MGI Sequence Detail 44516 C57BL/6J ±  kb
    transcript OTTMUST00000018297 VEGA | MGI Sequence Detail 4021 Not Applicable  
    polypeptide OTTMUSP00000008412 VEGA | MGI Sequence Detail 334 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      373 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 51
      Genomic 2
      cDNA 48
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 3
      Phenotypes 11
    • Earliest
      J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
    • Latest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/11/2018
    MGI 6.12     		The Jackson Laboratory