Slc35d1
Gene Detail

Symbol

Name
ID

Slc35d1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
MGI:2140361

Synonyms

UGTREL7

Feature Type

protein coding gene

Genetic Map

Chromosome 4
47.43 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr4:103170649-103215164 bp, - strand From VEGA annotation of GRCm38   44516 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:22870  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc35d1

Human
homologs

Human Homolog		SLC35D1, solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
NCBI Gene ID		23169
neXtProt AC		NX_Q9NTN3
Human Synonyms		UGTREL7
Human Chr (Location)		1p32-p31; chr1:66999332-67054397 (-)  GRCh38
Disease Associations		(1) Diseases Associated with Human SLC35D1

Mutations,
alleles, and
phenotypes

All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Genomic Mutations involving Slc35d1 (1)
Incidental mutations (data from Mutagenetix , APF )
 

Mice homozygous for a null allele exhibit neonatal lethality and chondrodystrophy associated with impaired chondroitin sulfate biosynthesis.

 
Human Diseases Modeled in Mice Using Slc35d1 (1)    Mutations Annotated to Human Diseases (1)   

Interactions

Slc35d1 interacts with 291 markers (Mir1b, Mir7-1, Mir7-2, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (6 annotations)

Process	chondroitin sulfate biosynthetic process, embryonic skeletal system development, ...
Component	endoplasmic reticulum
Function	pyrimidine nucleotide-sugar transmembrane transporter activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)

Data Summary: Results (1)    Tissues (1)    Images (1)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	1

cDNA source data(46)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(49) Genomic(1) cDNA(47) Primer pair(1)
Microarray probesets(3)

Other database
links

VEGA Gene Model	OTTMUSG00000008067 (Evidence)
Ensembl Gene Model	ENSMUSG00000028521 (Evidence)
Entrez Gene	242585 (Evidence)
UniGene	281800
DFCI	TC1583567, TC1658270, TC1626520, TC1606398, TC1599558
DoTS	DT.97358451, DT.94127005, DT.532037, DT.94127003, DT.94126999, DT.91361526, DT.91564158
NIA Mouse Gene Index	U025311
Consensus CDS Project	CCDS18409.1
International Mouse Knockout Project Status	Slc35d1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000008067	VEGA Gene Model | MGI Sequence Detail	44516	C57BL/6J
transcript	OTTMUST00000018297	VEGA | MGI Sequence Detail	4021	Not Applicable
polypeptide	OTTMUSP00000008412	VEGA | MGI Sequence Detail	334	Not Applicable

All sequences(69) RefSeq(7) UniProt(18)

Polymorphisms

SNPs within 2kb(371 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR004853	Domain of unknown function DUF250

References

(Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)
Disease annotation references (1)