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Slc35d1 Gene Detail
Summary
  • Symbol
    Slc35d1
  • Name
    solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
  • Synonyms
    UGTREL7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140361
    NCBI Gene: 242585
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:103170649-103215164 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 47.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    373 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140361
 protein coding gene Chr4:103170649-103215368 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028506
 protein coding gene Chr4:103584994-103630177 (-)
A/J MGP_AJ_G0028469
 protein coding gene Chr4:99970938-100016038 (-)
AKR/J MGP_AKRJ_G0028416
 protein coding gene Chr4:102397672-102442329 (-)
BALB/cJ MGP_BALBcJ_G0028488
 protein coding gene Chr4:100168968-100213512 (-)
C3H/HeJ MGP_C3HHeJ_G0028202
 protein coding gene Chr4:103177145-103222005 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028928
 protein coding gene Chr4:107495277-107539576 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026219
 protein coding gene Chr4:95322463-95366738 (-)
CAST/EiJ MGP_CASTEiJ_G0027638
 protein coding gene Chr4:100939529-100985459 (-)
CBA/J MGP_CBAJ_G0028171
 protein coding gene Chr4:110898661-110946634 (-)
DBA/2J MGP_DBA2J_G0028319
 protein coding gene Chr4:99625007-99669018 (-)
FVB/NJ MGP_FVBNJ_G0028286
 protein coding gene Chr4:98473280-98517763 (-)
LP/J MGP_LPJ_G0028420
 protein coding gene Chr4:103864625-103908958 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028313
 protein coding gene Chr4:116343257-116387547 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028963
 protein coding gene Chr4:102611916-102657222 (-)
PWK/PhJ MGP_PWKPhJ_G0027364
 protein coding gene Chr4:97839420-97884864 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027188
 protein coding gene Chr4:100033168-100073990 (-)
WSB/EiJ MGP_WSBEiJ_G0027718
 protein coding gene Chr4:102778299-102823677 (-)



Homology
more
  • Human Ortholog
    SLC35D1, solute carrier family 35 member D1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC35D1, solute carrier family 35 member D1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SHNKND, UGTREL7
  • Links
    NCBI Gene ID: 23169
    neXtProt AC: NX_Q9NTN3
    UniProt: Q9NTN3

  • Chr Location
    1p31.3; chr1:66999332-67054397 (-)  GRCh38.p7
Human Diseases
more
  • Diseases
    1 with Slc35d1 mouse models; 1 with human SLC35D1 associations

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit neonatal lethality and chondrodystrophy associated with impaired chondroitin sulfate biosynthesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
    1
  • Tissues
    1
  • cDNA Data
    47
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028521 Ensembl Gene Model | MGI Sequence Detail 44516 C57BL/6J ±  kb
    transcript ENSMUST00000036195 Ensembl | MGI Sequence Detail 4021 Not Applicable  
    polypeptide ENSMUSP00000037617 Ensembl | MGI Sequence Detail 334 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 51
      Genomic 2
      cDNA 48
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/13/2018
    MGI 6.13     		The Jackson Laboratory