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Slc35d1 Gene Detail
Summary
  • Symbol
    Slc35d1
  • Name
    solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
  • Synonyms
    UGTREL7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140361
    NCBI Gene: 242585
Location & Maps
more
  • Sequence Map
    Chr4:103170649-103215164 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      44516 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SLC35D1, solute carrier family 35 member D1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC35D1, solute carrier family 35 member D1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    UGTREL7
  • Links
    NCBI Gene ID: 23169
    neXtProt AC: NX_Q9NTN3

  • Chr Location
    1p31.3; chr1:66999332-67054397 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with Slc35d1 mouse models; 1 with human SLC35D1 associations

Human Disease Mouse Models
       Schneckenbecken Dysplasia   OMIM: 269250 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Slc35d1
  • Incidental Mutations
Mice homozygous for a null allele exhibit neonatal lethality and chondrodystrophy associated with impaired chondroitin sulfate biosynthesis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008067 VEGA Gene Model | MGI Sequence Detail 44516 C57BL/6J ±  kb
transcript OTTMUST00000018297 VEGA | MGI Sequence Detail 4021 Not Applicable  
polypeptide OTTMUSP00000008412 VEGA | MGI Sequence Detail 334 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    373 from dbSNP Build 142
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR004853 Sugar phosphate transporter domain
Molecular
Reagents
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  • All nucleic 50
    Genomic 1
    cDNA 48
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory