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Suco
Gene Detail
 Symbol
Name
ID
Suco
SUN domain containing ossification factor
MGI:2138346
Synonyms AI848100, Opt, osteopotentia
Feature Type protein coding gene
Genetic Map
Chromosome 1
69.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:161816112-161876661 bp, - strand
From NCBI annotation of GRCm38

  60550 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32212  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Suco

Human
homologs
Human Homolog SUCO, SUN domain containing ossification factor
NCBI Gene ID 51430
neXtProt AC  NX_Q9UBS9
Human Synonyms  C1orf9, CH1, OPT, SLP1
Human Chr (Location)  1q24; chr1:172532349-172611833 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(9) Targeted(2)
Incidental mutations (data from APF )
 
Mice homozygous for a mutation in this gene display background strain-dependent neonatal and postnatal lethality, and impaired osteoblast differentiation resulting in impaired bone formation, brittle bones, and impaired fracture repair.
 
Human Diseases Modeled Using Mouse Suco (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(3)
Interactions
Suco interacts with 365 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process multicellular organismal development, ossification, ...
Component endoplasmic reticulum, integral component of membrane, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(86)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(86) cDNA(86)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000040297 (Evidence)
Entrez Gene226551 (Evidence)
UniGene170002
DFCITC1581174, TC1607314, TC1607839
DoTSDT.101254355, DT.101387627, DT.110923616, DT.97352134
Consensus CDS ProjectCCDS48415.1
International Mouse Knockout Project StatusSuco
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 226551 NCBI Gene Model | MGI Sequence Detail 60550 C57BL/6J ±  kb
transcript NM_172645 RefSeq | MGI Sequence Detail 6308 C57BL/6 
polypeptide Q8C341 UniProt | EBI | MGI Sequence Detail 1250 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(18) UniProt(2)
Polymorphisms SNPs within 2kb(369 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008979 Galactose-binding domain-like
InterPro IPR012919 Sad1/UNC-like, C-terminal
Protein Ontology PR:000032354 SUN domain-containing ossification factor
Graphical View of Protein Domain Structure
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)
Disease annotation references (1)
Other
accession IDs
MGI:2138413

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory