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Suco
Gene Detail
Symbol

Name
ID
Suco
SUN domain containing ossification factor
MGI:2138346
Synonyms
AI848100, Opt, osteopotentia
Feature Type
protein coding gene
Genetic Map
Chromosome 1
69.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:161816114-161876682 bp, - strand
From VEGA annotation of GRCm38

  60569 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32212  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SUCO
Gene Tree: Suco

Human
homologs
SUCO, SUN domain containing ossification factor
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 51430
neXtProt AC: NX_Q9UBS9

Human Synonyms: C1orf9, CH1, OPT, SLP1

Human Chr (Location): 1q24; chr1:172532349-172611833 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(9) Targeted(2)
Incidental mutations (data from APF , CvDC )
 
Mice homozygous for a mutation in this gene display background strain-dependent neonatal and postnatal lethality, and impaired osteoblast differentiation resulting in impaired bone formation, brittle bones, and impaired fracture repair.
 
Human Diseases Modeled in Mice Using Suco (1)    Mutations Annotated to Human Diseases (1)    Phenotype Images(3)
Interactions
Suco interacts with 365 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process multicellular organismal development, ossification, ...
Component endoplasmic reticulum, integral component of membrane, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(86)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase suco ; ZFIN suco    NEW 
Molecular
reagents
All nucleic(86) cDNA(86)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000050995 (Evidence)
Ensembl Gene Model ENSMUSG00000040297 (Evidence)
Entrez Gene 226551 (Evidence)
UniGene 170002
DFCI TC1607839, TC1607314, TC1581174
DoTS DT.101254355, DT.101387627, DT.110923616, DT.97352134
NIA Mouse Gene Index U021961, U352660
Consensus CDS Project CCDS48415.1
International Mouse Phenotyping Consortium Status Suco
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000050995 VEGA Gene Model | MGI Sequence Detail 60569 C57BL/6J ±  kb
transcript OTTMUST00000129303 VEGA | MGI Sequence Detail 6327 Not Applicable 
polypeptide OTTMUSP00000069478 VEGA | MGI Sequence Detail 1254 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(18) UniProt(4)
Polymorphisms
SNPs within 2kb(369 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008979 Galactose-binding domain-like
InterPro IPR012919 Sad1/UNC-like, C-terminal
Protein Ontology PR:000032354 SUN domain-containing ossification factor
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)
Disease annotation references (1)
Other
accession IDs
MGI:2138413

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory