Suco Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Suco
SUN domain containing ossification factor
MGI:2138346

47 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Suco^em1(IMPC)Bay/Suco^em1(IMPC)Bay C57BL/6N-Suco^em1(IMPC)Bay/BayMmucd	preweaning lethality, complete penetrance	J:211773
Suco^{Gt(KST050)Byg}/Suco^{Gt(KST050)Byg} involves: 129P2/OlaHsd * C57BL/6	neonatal lethality, complete penetrance	J:159823
	respiratory distress	J:159823
Suco^{Gt(KST050)Byg}/Suco^{Gt(KST050)Byg} involves: 129P2/OlaHsd * C57BL/6 * CD-1	abnormal bone collagen fibril morphology	J:159823
	abnormal bone healing	J:159823
	abnormal bone ossification	J:159823
	abnormal bone remodeling	J:159823
	abnormal compact bone morphology	J:159823
	abnormal cranium morphology	J:159823
	abnormal gait	J:159823
	abnormal joint morphology	J:159823
	abnormal long bone morphology	J:159823
	abnormal neurocranium morphology	J:159823
	abnormal osteoblast morphology	J:159823
	abnormal osteoblast physiology	J:159823
	abnormal osteoclast physiology	J:159823
	abnormal renal glomerulus morphology	J:159823
	abnormal skeleton development	J:159823
	abnormal skeleton physiology	J:159823
	abnormal trabecular bone morphology	J:159823
	decreased body size	J:159823
	decreased bone mass	J:159823
	decreased bone trabecula number	J:159823
	decreased circulating insulin-like growth factor I level	J:159823
	decreased circulating osteocalcin level	J:159823
	decreased compact bone thickness	J:159823
	decreased fetal size	J:159823
	decreased osteoclast cell number	J:159823
	decreased trabecular bone connectivity density	J:159823
	decreased trabecular bone thickness	J:159823
	delayed bone ossification	J:159823
	delayed endochondral bone ossification	J:159823
	delayed intramembranous bone ossification	J:159823
	fragile skeleton	J:159823
	hypoglycemia	J:159823
	impaired osteoblast differentiation	J:159823
	impaired righting response	J:159823
	increased circulating alkaline phosphatase level	J:159823
	increased osteoblast apoptosis	J:159823
	increased osteocyte number	J:159823
	internal hemorrhage	J:159823
	neonatal lethality, incomplete penetrance	J:159823
	postnatal growth retardation	J:159823
	postnatal lethality, complete penetrance	J:159823
	respiratory distress	J:159823
	spinal hemorrhage	J:159823
	thin neurocranium	J:159823
	wide cranial sutures	J:159823

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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