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Csmd1 Gene Detail
Summary
  • Symbol
    Csmd1
  • Name
    CUB and Sushi multiple domains 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137383
    NCBI Gene: 94109
  • Gene Overview
    MyGene.info: CSMD1
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:15892538-17535385 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 8.38 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    14512 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137383
protein coding gene Chr8:15892537-17535586 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033402
protein coding gene Chr8:13270563-14951995 (-)
A/J MGP_AJ_G0033383
protein coding gene Chr8:12860018-14470202 (-)
AKR/J MGP_AKRJ_G0033313
protein coding gene Chr8:13182907-14863639 (-)
BALB/cJ MGP_BALBcJ_G0033383
protein coding gene Chr8:12932465-14561481 (-)
C3H/HeJ MGP_C3HHeJ_G0033096
protein coding gene Chr8:13408290-15073461 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033895
protein coding gene Chr8:13746744-15462188 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030861
protein coding gene Chr8:12228762-13825715 (-)
CAST/EiJ MGP_CASTEiJ_G0032418
protein coding gene Chr8:13201943-14916891 (-)
CBA/J MGP_CBAJ_G0033069
protein coding gene Chr8:14310920-16113205 (-)
DBA/2J MGP_DBA2J_G0033223
protein coding gene Chr8:12778730-14396078 (-)
FVB/NJ MGP_FVBNJ_G0033171
protein coding gene Chr8:12823928-14446062 (-)
LP/J MGP_LPJ_G0033316
protein coding gene Chr8:13267508-14963124 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033208
protein coding gene Chr8:14519742-16300250 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033912
protein coding gene Chr8:13242568-14884616 (-)
PWK/PhJ MGP_PWKPhJ_G0032131
protein coding gene Chr8:12820068-14437996 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031972
protein coding gene Chr8:13156090-14820621 (-)
WSB/EiJ MGP_WSBEiJ_G0032534
protein coding gene Chr8:13312266-14989773 (-)



Homology
more
  • Human Ortholog
    CSMD1, CUB and Sushi multiple domains 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CSMD1, CUB and Sushi multiple domains 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PPP1R24
  • Links
    NCBI Gene ID: 64478
    neXtProt AC: NX_Q96PZ7
    UniProt: Q96PZ7

  • Chr Location
    8p23.2; chr8:2935353-4995035 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Csmd1 mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice exhibit normal pre-pulse inhibition, social interaction, sucrose preference and d-amphetamine sensitivity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 94109 NCBI Gene Model | MGI Sequence Detail 1642848 C57BL/6J ±  kb
    transcript NM_053171 RefSeq | MGI Sequence Detail 14278 C57BL/6  
    polypeptide Q923L3 UniProt | EBI | MGI Sequence Detail 3564 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 4
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Diseases 2
      Gene Ontology 2
      Phenotypes 10
    • Earliest
      J:70242 Sun PC, et al., Transcript map of the 8p23 putative tumor suppressor region. Genomics. 2001 Jul;75(1-3):17-25
    • Latest
      J:238535 Drgonova J, et al., Altered CSMD1 Expression Alters Cocaine-Conditioned Place Preference: Mutual Support for a Complex Locus from Human and Mouse Models. PLoS One. 2015;10(7):e0120908

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory