About   Help   FAQ
Abo Gene Detail
Summary
  • Symbol
    Abo
  • Name
    ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase)
  • Synonyms
    cis-AB transferase
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135738
    NCBI Gene: 80908
  • Gene Overview
    MyGene.info: ABO
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:26842503-26864979 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 19.06 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    99 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135738
protein coding gene Chr2:26842496-26864995 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025496
protein coding gene Chr2:24811731-24836513 (-)
A/J MGP_AJ_G0025473
protein coding gene Chr2:23860151-23892014 (-)
AKR/J MGP_AKRJ_G0025443
protein coding gene Chr2:24641210-24667087 (-)
BALB/cJ MGP_BALBcJ_G0025469
protein coding gene Chr2:23983671-24006405 (-)
C3H/HeJ MGP_C3HHeJ_G0025230
protein coding gene Chr2:24586828-24610614 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025913
protein coding gene Chr2:25629605-25667243 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023324
protein coding gene Chr2:22717553-22738983 (-)
CAST/EiJ MGP_CASTEiJ_G0024693
protein coding gene Chr2:24461018-24486448 (-)
CBA/J MGP_CBAJ_G0025208
protein coding gene Chr2:26512894-26536427 (-)
DBA/2J MGP_DBA2J_G0025341
protein coding gene Chr2:23684539-23707271 (-)
FVB/NJ MGP_FVBNJ_G0025303
protein coding gene Chr2:23439795-23462894 (-)
LP/J MGP_LPJ_G0025427
protein coding gene Chr2:24755650-24779935 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025334
protein coding gene Chr2:26598122-26623091 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025972
protein coding gene Chr2:24588618-24610961 (-)
PWK/PhJ MGP_PWKPhJ_G0024441
protein coding gene Chr2:23479948-23502490 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024241
protein coding gene Chr2:24734229-24756541 (-)
WSB/EiJ MGP_WSBEiJ_G0024762
protein coding gene Chr2:24705998-24729300 (-)



Homology
more
  • Human Ortholog
    ABO, ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ABO, ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    A3GALNT, A3GALT1, GTB, NAGAT
  • Links
    NCBI Gene ID: 28
    neXtProt AC: NX_P16442
    UniProt: P16442

  • Chr Location
    9q34.2; chr9:133255176-133275214 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015787 Ensembl Gene Model | MGI Sequence Detail 22477 C57BL/6J ±  kb
transcript ENSMUST00000114045 Ensembl | MGI Sequence Detail 1811 Not Applicable  
polypeptide ENSMUSP00000109679 Ensembl | MGI Sequence Detail 334 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 2
    cDNA 7

    Microarray probesets 5
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:68988 Yamamoto M, et al., Murine equivalent of the human histo-blood group ABO gene is a cis-AB gene and encodes a glycosyltransferase with both A and B transferase activity. J Biol Chem. 2001 Apr 27;276(17):13701-8
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/04/2018
MGI 6.13
The Jackson Laboratory