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Slc1a4 Gene Detail
Summary
  • Symbol
    Slc1a4
  • Name
    solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
  • Synonyms
    ASCT1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135601
    NCBI Gene: 55963
  • Gene Overview
    MyGene.info: SLC1A4
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:20302180-20332713 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 12.97 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    521 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135601
protein coding gene Chr11:20302180-20332713 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018066
protein coding gene Chr11:17819333-17851105 (-)
A/J MGP_AJ_G0018039
protein coding gene Chr11:17226221-17258991 (-)
AKR/J MGP_AKRJ_G0018003
protein coding gene Chr11:17835357-17867216 (-)
BALB/cJ MGP_BALBcJ_G0018007
protein coding gene Chr11:17343992-17374083 (-)
C3H/HeJ MGP_C3HHeJ_G0017821
protein coding gene Chr11:17728756-17758017 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018459
protein coding gene Chr11:18630164-18663868 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016117
protein coding gene Chr11:16217542-16246773 (-)
CAST/EiJ MGP_CASTEiJ_G0017382
protein coding gene Chr11:17688674-17720880 (-)
CBA/J MGP_CBAJ_G0017795
protein coding gene Chr11:19440764-19477320 (-)
DBA/2J MGP_DBA2J_G0017905
protein coding gene Chr11:17173363-17200657 (-)
FVB/NJ MGP_FVBNJ_G0017897
protein coding gene Chr11:16913770-16943265 (-)
LP/J MGP_LPJ_G0017976
protein coding gene Chr11:17993137-18025540 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017923
protein coding gene Chr11:19892107-19923991 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018500
protein coding gene Chr11:17920096-17951706 (-)
PWK/PhJ MGP_PWKPhJ_G0017162
protein coding gene Chr11:17182700-17212263 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016960
protein coding gene Chr11:17642462-17675036 (-)
WSB/EiJ MGP_WSBEiJ_G0017436
protein coding gene Chr11:17578488-17608935 (-)



Homology
more
  • Human Ortholog
    SLC1A4, solute carrier family 1 member 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC1A4, solute carrier family 1 member 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ASCT1, SATT, SPATCCM
  • Links
    NCBI Gene ID: 6509
    neXtProt AC: NX_P43007
    UniProt: P43007

  • Chr Location
    2p14; chr2:64988445-65023865 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 55963 NCBI Gene Model | MGI Sequence Detail 30534 C57BL/6J ±  kb
transcript NM_018861 RefSeq | MGI Sequence Detail 3926 C57BL/6  
polypeptide O35874 UniProt | EBI | MGI Sequence Detail 532 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 92
    cDNA 90
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144477
References
more
  • Summaries
    All 39
    Developmental Gene Expression 7
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory