Slc1a4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
MGI:2135601

25 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc1a4^em2Tmg/Slc1a4^em2Tmg involves: C57BL/6J	abnormal cerebral cortex morphology	J:344184
	abnormal corpus callosum morphology	J:344184
	abnormal response to novel object	J:344184
	normal behavior/neurological phenotype	J:344184
	decreased brain weight	J:344184
	normal growth/size/body region phenotype	J:344184
	microcephaly	J:344184
Slc1a4^tm1.1Wechu/Slc1a4^tm1.1Wechu C57BL/6J-Slc1a4^tm1.1Hwolo	abnormal asymmetric synapse morphology	J:359113
	abnormal neuron mitochondrial morphology	J:359113
	abnormal postsynaptic density morphology	J:359113
	abnormal synaptic bouton morphology	J:359113
	decreased brain size	J:359113
	decreased brain weight	J:359113
	decreased corpus callosum size	J:359113
	decreased neocortex size	J:359113
	dilated lateral ventricle	J:359113
	excessive vocalization	J:359113
	normal growth/size/body region phenotype	J:359113
	impaired limb coordination	J:359113
	increased neuron apoptosis	J:359113
	increased tau protein phosphorylation	J:359113
	microcephaly	J:359113
	muscle weakness	J:359113
	normal nervous system phenotype	J:359113
	neurodegeneration	J:359113
Slc1a4^{tm1e(KOMP)Wtsi}/Slc1a4^{tm1e(KOMP)Wtsi} C57BL/6N-Slc1a4^{tm1e(KOMP)Wtsi}/Wtsi	decreased circulating serum albumin level	J:211773
	improved glucose tolerance	J:211773
	increased red blood cell distribution width	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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