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Pcdhga12
Gene Detail
Symbol

Name
ID
Member of
Pcdhga12
protocadherin gamma subfamily A, 12
MGI:1935229
Pcdhg cluster
Synonyms
pc2c, Pcdh13
Feature Type
protein coding gene
Genetic Map
Chromosome 18
19.63 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr18:37765580-37841873 bp, + strand
From VEGA annotation of GRCm38

  76294 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:134588  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog

Gene Tree: Pcdhga12

Human
homologs
Human Homolog   PCDHGA12, protocadherin gamma subfamily A, 12
NCBI Gene ID 26025
neXtProt AC  NX_O60330
Human Synonyms  CDH21, FIB3, PCDH-GAMMA-A12
Human Chr (Location)  5q31; chr5:141430591-141512979 (+)  GRCh38.p2
Mutations,
alleles, and
phenotypes
Incidental mutations (data from APF , CvDC )
Interactions
Pcdhga12 interacts with 270 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Component cell-cell junction, membrane, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (151)    Tissues (35)    Images (31)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 151
cDNA source data(7)
External Resources: Allen Institute   GEO  
Molecular
reagents
All nucleic(11) Genomic(2) cDNA(8) Primer pair(1)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000050866 (Evidence)
Ensembl Gene ModelENSMUSG00000102428 (Evidence)
Entrez Gene93724 (Evidence)
Consensus CDS ProjectCCDS29191.1
International Mouse Knockout Project StatusPcdhga12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000050866 VEGA Gene Model | MGI Sequence Detail 76294 C57BL/6J ±  kb
transcript OTTMUST00000128882 VEGA | MGI Sequence Detail 5080 Not Applicable 
polypeptide OTTMUSP00000069306 VEGA | MGI Sequence Detail 932 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(7)
Polymorphisms
SNPs within 2kb(701 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002126 Cadherin
InterPro IPR020894 Cadherin conserved site
InterPro IPR015919 Cadherin-like
InterPro IPR013164 Cadherin, N-terminal
References
(Earliest) J:60527 Hirano S, et al., Protocadherin 2C: a new member of the protocadherin 2 subfamily expressed in a redundant manner with OL-protocadherin in the developing brain. Biochem Biophys Res Commun. 1999 Jul 14;260(3):641-5
(Latest) J:195283 Ledderose J, et al., Maturation of postnatally generated olfactory bulb granule cells depends on functional gamma-protocadherin expression. Sci Rep. 2013;3:1514
All references(22)
Other
accession IDs
MGI:1353490

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory