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Pcdhgc5 Gene Detail
Summary
  • Symbol
    Pcdhgc5
  • Name
    protocadherin gamma subfamily C, 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1935205
    NCBI Gene: 93708
  • Member of
    Pcdhg cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37952599-37974926 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    480 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1935205
 protein coding gene Chr18:37952566-37974926 (+)
129S1/SvImJ ENSMUSGG00200054411
 protein coding gene Chr18:34947468-34974253 (+)
A/J ENSMUSGG00195055432
 protein coding gene Chr18:35098158-35124953 (+)
AKR/J ENSMUSGG00220054546
 protein coding gene Chr18:35068100-35094891 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ ENSMUSGG00215055359
 protein coding gene Chr18:34817692-34844495 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022201
 protein coding gene Chr18:35006152-35028291 (+)
CAST/EiJ ENSTCUGG00005053861
 protein coding gene Chr18:34678382-34705126 (+)
CBA/J ENSMUSGG00210054515
 protein coding gene Chr18:35089814-35116624 (+)
DBA/2J ENSMUSGG00185057549
 protein coding gene Chr18:35024430-35051237 (+)
FVB/NJ no annotation
JF1/MsJ ENSUMUGG00000058276
 protein coding gene Chr18:35158807-35185621 (+)
LP/J ENSMUSGG00230055516
 protein coding gene Chr18:37141617-37168405 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ ENSMUSGG00225055270
 protein coding gene Chr18:37048431-37075240 (+)
PWK/PhJ ENSLUMGG00010053924
 protein coding gene Chr18:35302377-35329154 (+)
SPRET/EiJ ENSMSPG00010016779
 protein coding gene Chr18:35185840-35364461 (+)
WSB/EiJ ENSIUOGG00005054321
 protein coding gene Chr18:34804246-34831048 (+)



Homology
more
  • Human Ortholog
    PCDHGC5, protocadherin gamma subfamily C, 5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHGC5, protocadherin gamma subfamily C, 5
  • Synonyms
    PCDH-GAMMA-C5
  • Links
    NCBI Gene ID: 56097
    UniProt: Q9Y5F6

  • Chr Location
    5q31.3; chr5:141489081-141512975 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    614
  • Tissues
    6
  • cDNA Data
    2
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93708 NCBI Gene Model | MGI Sequence Detail 22328 C57BL/6J ±  kb
transcript NM_033583 RefSeq | MGI Sequence Detail 4708 C57BL/6  
polypeptide NP_291061 RefSeq | MGI Sequence Detail 944 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 2
    cDNA 2
    Primer pair 2
References
more
  • Summaries
    All 29
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:86878 Wu Q, et al., A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90
  • Latest
    J:367744 Sun X, et al., Cell Adhesion Molecule Protocadherin-gammaC5 Ameliorates Abeta Plaque Pathogenesis by Modulating Astrocyte Function in Alzheimer's Disease. J Neurosci. 2025 Mar 5;45(10)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory