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Rtn1 Gene Detail
Summary
  • Symbol
    Rtn1
  • Name
    reticulon 1
  • Synonyms
    0710005K15Rik, 4930441F12Rik, MGC:40985, Nsp, Rtn1-a, Rtn1-b, Rtn1-c
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933947
    NCBI Gene: 104001
  • Gene Overview
    MyGene.info: RTN1
Location & Maps
more
  • Sequence Map
    Chr12:72211752-72409054 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      197303 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 30.20 cM, cytoband C3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RTN1, reticulon 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RTN1, reticulon 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NSP
  • Links
    NCBI Gene ID: 6252
    neXtProt AC: NX_Q16799

  • Chr Location
    14q23.1; chr14:59595976-59870839 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 49654
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RTN1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Targeted
    3
  • Genomic Mutations
    1 involving Rtn1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016329 VEGA Gene Model | MGI Sequence Detail 197303 C57BL/6J ±  kb
transcript OTTMUST00000039235 VEGA | MGI Sequence Detail 3629 Not Applicable  
polypeptide OTTMUSP00000017535 VEGA | MGI Sequence Detail 780 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1929 from dbSNP Build 142
Protein
Information
less
  • UniProt
    7 Sequences
  • InterPro Domains
    IPR003388 Reticulon
Molecular
Reagents
less
  • All nucleic 129
    cDNA 128
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1913343, MGI:1926049, MGI:2145135
References
more
  • Summaries
    All 46
    Developmental Gene Expression 8
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:46660 Geisler JG, et al., Molecular cloning of a novel mouse gene with predominant muscle and neural expression. Mamm Genome. 1998 Apr;9(4):274-82
  • Latest
    J:202429 Kaya L, et al., Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons. Biochim Biophys Acta. 2013 Jun;1833(6):1421-33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory