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Rtn1 Gene Detail
Summary
  • Symbol
    Rtn1
  • Name
    reticulon 1
  • Synonyms
    0710005K15Rik, 4930441F12Rik, MGC:40985, Nsp, Rtn1-a, Rtn1-b, Rtn1-c
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933947
    NCBI Gene: 104001
  • Gene Overview
    MyGene.info: RTN1
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:72211752-72409054 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 30.20 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1929 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933947
protein coding gene Chr12:72211749-72409054 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019824
protein coding gene Chr12:72030800-72238674 (-)
A/J MGP_AJ_G0019782
protein coding gene Chr12:69347685-69545943 (-)
AKR/J MGP_AKRJ_G0019758
protein coding gene Chr12:71431703-71639422 (-)
BALB/cJ MGP_BALBcJ_G0019762
protein coding gene Chr12:69837388-70030804 (-)
C3H/HeJ MGP_C3HHeJ_G0019567
protein coding gene Chr12:71890709-72090269 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020214
protein coding gene Chr12:74306868-74516718 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017834
protein coding gene Chr12:66824210-67014800 (-)
CAST/EiJ MGP_CASTEiJ_G0019119
protein coding gene Chr12:66649815-66863153 (-)
CBA/J MGP_CBAJ_G0019537
protein coding gene Chr12:77072782-77293561 (-)
DBA/2J MGP_DBA2J_G0019653
protein coding gene Chr12:69249526-69448102 (-)
FVB/NJ MGP_FVBNJ_G0019640
protein coding gene Chr12:68123146-68318013 (-)
LP/J MGP_LPJ_G0019725
protein coding gene Chr12:72043688-72251539 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019679
protein coding gene Chr12:80248924-80469220 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020249
protein coding gene Chr12:70939145-71143990 (-)
PWK/PhJ MGP_PWKPhJ_G0018884
protein coding gene Chr12:63546568-63744606 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018679
protein coding gene Chr12:65341116-65549183 (-)
WSB/EiJ MGP_WSBEiJ_G0019170
protein coding gene Chr12:71533390-71733778 (-)



Homology
more
  • Human Ortholog
    RTN1, reticulon 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RTN1, reticulon 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NSP
  • Links
    NCBI Gene ID: 6252
    neXtProt AC: NX_Q16799
    UniProt: Q16799

  • Chr Location
    14q23.1; chr14:59595976-59871288 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 49654
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RTN1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021087 Ensembl Gene Model | MGI Sequence Detail 197303 C57BL/6J ±  kb
transcript ENSMUST00000078505 Ensembl | MGI Sequence Detail 3629 Not Applicable  
polypeptide ENSMUSP00000077594 Ensembl | MGI Sequence Detail 780 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • InterPro Domains
    IPR003388 Reticulon
Molecular
Reagents
less
  • All nucleic 130
    cDNA 129
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1913343, MGI:1926049, MGI:2145135
References
more
  • Summaries
    All 52
    Developmental Gene Expression 8
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:46660 Geisler JG, et al., Molecular cloning of a novel mouse gene with predominant muscle and neural expression. Mamm Genome. 1998 Apr;9(4):274-82
  • Latest
    J:253342 McGonigle TA, et al., Reticulon-1 and Reduced Migration toward Chemoattractants by Macrophages Differentiated from the Bone Marrow of Ultraviolet-Irradiated and Ultraviolet-Chimeric Mice. J Immunol. 2018 Jan 1;200(1):260-270

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory