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Mmp1b
Gene Detail
 Symbol
Name
ID
Mmp1b
matrix metallopeptidase 1b (interstitial collagenase)
MGI:1933847
Synonyms Mcol-B
Feature Type protein coding gene
Genetic Map
Chromosome 9
2.46 cM, cytoband A1-A2
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:7368239-7388047 bp, - strand
From VEGA annotation of GRCm38

  19809 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:130791  Vertebrate Homology Class
1 mouse; 2 rat

Protein SuperFamily: matrix metalloproteinase, stromelysin type
Gene Tree: Mmp1b

Alleles
and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process collagen catabolic process, proteolysis
Component collagen trimer, extracellular matrix, ...
Function calcium ion binding, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (14)    Tissues (12)    Images (3)
Theiler Stages: 13, 15, 17, 19, 21, 23, 25, 28
Assay TypeResults
RNA in situ 5
RT-PCR 9
cDNA source data(3)
External Resources: GEO   ArrayExpress
Molecular
reagents
All nucleic(9) Genomic(3) cDNA(3) Primer pair(1) Other(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000027386 (Evidence)
Ensembl Gene ModelENSMUSG00000041620 (Evidence)
Entrez Gene83996 (Evidence)
UniGene379271
DoTSDT.91331916
EC3.4.24.7
Consensus CDS ProjectCCDS22805.1
International Mouse Knockout Project StatusMmp1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027386 VEGA Gene Model | MGI Sequence Detail 19809 C57BL/6J ±  kb
transcript OTTMUST00000067734 VEGA | MGI Sequence Detail 1449 Not Applicable 
polypeptide OTTMUSP00000034122 VEGA | MGI Sequence Detail 463 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(50 from dbSNP Build 137)    SNPs within 2kb including multiple locations(70)
Protein-related
information
ResourceIDDescription
InterPro IPR018486 Hemopexin, conserved site
InterPro IPR000585 Hemopexin-like domain
InterPro IPR018487 Hemopexin-like repeats
InterPro IPR024079 Metallopeptidase, catalytic domain
InterPro IPR021190 Peptidase M10A
InterPro IPR021158 Peptidase M10A, cysteine switch, zinc binding site
InterPro IPR016293 Peptidase M10A, metazoans
InterPro IPR001818 Peptidase M10, metallopeptidase
InterPro IPR006026 Peptidase, metallopeptidase
InterPro IPR002477 Peptidoglycan binding-like
Protein Ontology PR:000010915 interstitial collagenase B
References (Earliest) J:68613 Balbin M, et al., Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation. J Biol Chem. 2001 Mar 30;276(13):10253-62
(Latest) J:157304 Tsuzurahara F, et al., The role of macrophages in the disappearance of Meckel's cartilage during mandibular development in mice. Acta Histochem. 2011;113(2):194-200
All references(21)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory