Mmp1b
Gene Detail

Symbol Name ID

Mmp1b matrix metallopeptidase 1b (interstitial collagenase) MGI:1933847

Synonyms

Mcol-B

Feature Type

protein coding gene

Genetic Map

Chromosome 9

2.46 cM, cytoband A1-A2
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr9:7368239-7388047 bp, - strand From VEGA annotation of GRCm38   19809 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:130791  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: matrix metalloproteinase, stromelysin type
Gene Tree: Mmp1b

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	collagen catabolic process, metabolic process, ...
Component	collagen, extracellular matrix, ...
Function	calcium ion binding, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (14)    Tissues (12)    Images (3)
Theiler Stages: 13, 15, 17, 19, 21, 23, 25, 28

Assay Type	Results
RNA in situ	5
RT-PCR	9

cDNA source data(3)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(9) Genomic(3) cDNA(3) Primer pair(1) Other(2)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000027386 (Evidence)
Ensembl Gene Model	ENSMUSG00000041620 (Evidence)
Entrez Gene	83996 (Evidence)
UniGene	379271
DoTS	DT.91331916
EC	3.4.24.7
Consensus CDS Project	CCDS22805.1
International Mouse Knockout Project Status	Mmp1b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027386	VEGA Gene Model | MGI Sequence Detail	19809	C57BL/6J
transcript	OTTMUST00000067734	VEGA | MGI Sequence Detail	1449	Not Applicable
polypeptide	OTTMUSP00000034122	VEGA | MGI Sequence Detail	463	Not Applicable

All sequences(17) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(33 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000585	Hemopexin/matrixin
InterPro	IPR018486	Hemopexin/matrixin, conserved site
InterPro	IPR018487	Hemopexin/matrixin, repeat
InterPro	IPR024079	Metallopeptidase, catalytic domain
InterPro	IPR021158	Peptidase M10A, cysteine switch, zinc binding site
InterPro	IPR021190	Peptidase M10A, matrix metallopeptidase
InterPro	IPR016293	Peptidase M10A, matrix metallopeptidase, stromelysin type
InterPro	IPR001818	Peptidase M10, metallopeptidase
InterPro	IPR006026	Peptidase, metallopeptidase
InterPro	IPR002477	Peptidoglycan binding-like
Protein Ontology	PR:000010915	interstitial collagenase B

References

(Earliest) J:68613 Balbin M, et al., Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation. J Biol Chem. 2001 Mar 30;276(13):10253-62
(Latest) J:157304 Tsuzurahara F, et al., The role of macrophages in the disappearance of Meckel's cartilage during mandibular development in mice. Acta Histochem. 2011;113(2):194-200
All references(21)