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Pole3 Gene Detail
Summary
  • Symbol
    Pole3
  • Name
    polymerase (DNA directed), epsilon 3 (p17 subunit)
  • Synonyms
    1810034K18Rik, YBL1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933378
    NCBI Gene: 59001
  • Gene Overview
    MyGene.info: POLE3
Location & Maps
more
  • Sequence Map
    Chr4:62522649-62525068 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2420 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 33.17 cM, cytoband C1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    POLE3, DNA polymerase epsilon 3, accessory subunit
  • Vertebrate Orthologs
    11
  • Human Ortholog
    POLE3, DNA polymerase epsilon 3, accessory subunit
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CHARAC17, CHRAC17, p17, YBL1
  • Links
    NCBI Gene ID: 54107
    neXtProt AC: NX_Q9NRF9

  • Chr Location
    9q33; chr9:113407235-113410749 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9694
    1 human;1 mouse;2 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: POLE3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    4
  • Targeted
    1
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009021 VEGA Gene Model | MGI Sequence Detail 2420 C57BL/6J ±  kb
transcript OTTMUST00000020463 VEGA | MGI Sequence Detail 1805 Not Applicable  
polypeptide OTTMUSP00000009375 VEGA | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    28 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR009072 Histone-fold
    IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1919274
References
more
  • Summaries
    All 31
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:65020 Bolognese F, et al., Cloning and characterization of the histone-fold proteins YBL1 and YCL1. Nucleic Acids Res. 2000 Oct 1;28(19):3830-8
  • Latest
    J:140465 Guo G, et al., Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory