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Tm6sf2 Gene Detail
Summary
  • Symbol
    Tm6sf2
  • Name
    transmembrane 6 superfamily member 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933210
    NCBI Gene: 107770
Location & Maps
more
  • Sequence Map
    Chr8:70072924-70080066 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7143 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 34.15 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TM6SF2, transmembrane 6 superfamily member 2
  • Vertebrate Orthologs
    12
  • Human Ortholog
    TM6SF2, transmembrane 6 superfamily member 2
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 53345
    neXtProt AC: NX_Q9BZW4

  • Chr Location
    19p13.11; chr19:19264365-19273265 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Tm6sf2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027309 VEGA Gene Model | MGI Sequence Detail 7143 C57BL/6J ±  kb
transcript OTTMUST00000067499 VEGA | MGI Sequence Detail 1446 Not Applicable  
polypeptide OTTMUSP00000033975 VEGA | MGI Sequence Detail 378 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    81 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000030705 transmembrane 6 superfamily member 2
  • InterPro Domains
    IPR033118 EXPERA domain
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 21
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:66727 Carim-Todd L, et al., Cloning of the novel gene TM6SF1 reveals conservation of clusters of paralogous genes between human chromosomes 15q24-->q26 and 19p13.3-->p12. Cytogenet Cell Genet. 2000;90(3-4):255-60
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory