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Ndel1
Gene Detail
Symbol

Name
ID
Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
MGI:1932915
Synonyms
2600006O07Rik, mNudel
Feature Type
protein coding gene
Genetic Map
Chromosome 11
42.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:68821434-68871858 bp, - strand
From VEGA annotation of GRCm38

  50425 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32567  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: NDEL1
Gene Tree: Ndel1

Human
homologs
NDEL1, nudE neurodevelopment protein 1-like 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 81565
neXtProt AC: NX_Q9GZM8

Human Synonyms: EOPA, MITAP1, NDE1L1, NDE2, NUDEL

Human Chr (Location): 17p13.1; chr17:8435852-8471708 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Gene trapped(13) Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ndel1 interacts with 273 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (70 annotations)
Process activation of GTPase activity, cell differentiation, ...
Component axon, axon hillock, ...
Function alpha-tubulin binding, beta-tubulin binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (18 records)
Data Summary: Results (216)    Tissues (140)    Images (48)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 207
Northern blot 2
Western blot 4
RT-PCR 3
cDNA source data(12)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase ndel1 ; ZFIN ndel1a, ndel1b    NEW 
Molecular
reagents
All nucleic(14) cDNA(12) Primer pair(2)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000005956 (Evidence)
Ensembl Gene Model ENSMUSG00000018736 (Evidence)
Entrez Gene 83431 (Evidence)
DFCI TC1586683, TC1619703, TC1572502
DoTS DT.97412112, DT.91570287, DT.101398454, DT.492802
NIA Mouse Gene Index U032947
Consensus CDS Project CCDS24870.1
International Mouse Phenotyping Consortium Status Ndel1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005956 VEGA Gene Model | MGI Sequence Detail 50425 C57BL/6J ±  kb
transcript OTTMUST00000013283 VEGA | MGI Sequence Detail 2382 Not Applicable 
polypeptide OTTMUSP00000006155 VEGA | MGI Sequence Detail 345 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(380 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006964 NUDE protein, C-terminal
Protein Ontology PR:000011052 nuclear distribution protein nudE-like 1
References
(Earliest) J:66487 Niethammer M, et al., NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron. 2000 Dec;28(3):697-711
(Latest) J:219862 Okamoto M, et al., DBZ regulates cortical cell positioning and neurite development by sustaining the anterograde transport of Lis1 and DISC1 through control of Ndel1 dual-phosphorylation. J Neurosci. 2015 Feb 18;35(7):2942-58
All references(67)
Other
accession IDs
MGI:1919693

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory