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Sequence Detail
ID/Version
Q9ERR1 Q9D0Q4 Q9EPT6 (UniProt | EBI) Last sequence update: 2006-06-13
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Nuclear distribution protein nudE-like 1;AltName: Full=Protein mNudE-like; Short=Protein Nudel; Short=mNudE-L;
Provider SWISS-PROT
Sequence
Polypeptide 345 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ndel1 nudE neurodevelopment protein 1 like 1 84 109 4 23
Sequence references in MGI J:66487 Niethammer M, et al., NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron. 2000 Dec;28(3):697-711
J:66505 Sasaki S, et al., A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron. 2000 Dec;28(3):681-96
J:68112 Sweeney KJ, et al., NudE-L, a novel Lis1-interacting protein, belongs to a family of vertebrate coiled-coil proteins. Mech Dev. 2001 Mar;101(1-2):21-33
J:84075 Toyo-oka K, et al., 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet. 2003 Jul;34(3):274-85
J:91559 Nguyen MD, et al., A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons. Nat Cell Biol. 2004 Jul;6(7):595-608
J:94756 Feng Y, et al., Mitotic spindle regulation by Nde1 controls cerebral cortical size. Neuron. 2004 Oct 14;44(2):279-93
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100552 Sasaki S, et al., Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Mol Cell Biol. 2005 Sep;25(17):7812-27
J:102751 Toyo-Oka K, et al., Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration. Hum Mol Genet. 2005 Nov 1;14(21):3113-28
J:119418 Yamaguchi N, et al., Expression of NUDEL in manchette and its implication in spermatogenesis. FEBS Lett. 2004 May 21;566(1-3):71-6
J:236517 Fujiwara T, et al., PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis. JCI Insight. 2016 Oct 20;1(17):e86330
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory