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Chst5
Gene Detail
Symbol

Name
ID
Chst5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
MGI:1931825
Synonyms
GST-4, I-GlcNAc6ST
Feature Type
protein coding gene
Genetic Map
Chromosome 8
58.11 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:111889135-111910199 bp, - strand
From NCBI annotation of GRCm38

  21065 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56927  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: carbohydrate sulfotransferase
Gene Tree: Chst5

Human
homologs
Human Homolog CHST6, carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
NCBI Gene ID 4166
neXtProt AC  NX_Q9GZX3
Human Synonyms  MCDC1
Human Chr (Location)  16q22; chr16:75473124-75495028 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CHST6
Mutations,
alleles, and
phenotypes
All mutations/alleles(47) : Gene trapped(43) Targeted(4)
Incidental mutations (data from APF )
 
Homozygous mutation of this gene results in thinner corneas that show abnormally close collagen fibrillar packing.
 
Phenotype Images(2)
Interactions
Chst5 interacts with 106 markers (Mir34a, Mir34b, Mir34c, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (110)    Tissues (98)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 110
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(8) Other(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000031952 (Evidence)
Entrez Gene56773 (Evidence)
UniGene432506
DFCITC1585393
DoTSDT.527549
NIA Mouse Gene IndexU030272
EC2.8.2.-
Consensus CDS ProjectCCDS22682.1
International Mouse Knockout Project StatusChst5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 56773 NCBI Gene Model | MGI Sequence Detail 21065 C57BL/6J ±  kb
transcript NM_019950 RefSeq | MGI Sequence Detail 1935 C57BL/6 
polypeptide Q9QUP4 UniProt | EBI | MGI Sequence Detail 395 Not Applicable 

For the selected sequences
All sequences(14) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(163 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016469 Carbohydrate sulfotransferase
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR000863 Sulfotransferase domain
Protein Ontology PR:000005478 carbohydrate sulfotransferase 5
Graphical View of Protein Domain Structure
References
(Earliest) J:57776 Lee JK, et al., Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue. Biochem Biophys Res Commun. 1999 Sep 24;263(2):543-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGI:2142470

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory