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Chst5
Gene Detail
 Symbol
Name
ID
Chst5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
MGI:1931825
Synonyms GST-4, I-GlcNAc6ST
Feature Type protein coding gene
Genetic Map
Chromosome 8
58.11 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:111889135-111910199 bp, - strand
From NCBI annotation of GRCm38

  21065 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56927  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: carbohydrate sulfotransferase
Gene Tree: Chst5

Human
homologs
Human Homolog CHST6, carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
NCBI Gene ID 4166
neXtProt AC  NX_Q9GZX3
Human Synonyms  MCDC1
Human Chr (Location)  16q22; chr16:75473124-75495028 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CHST6
Alleles
and
phenotypes
All alleles(47) : Gene trapped(43) Targeted(4)
Incidental mutations (data from APF )
 
Homozygous mutation of this gene results in thinner corneas that show abnormally close collagen fibrillar packing.
 
Phenotype Images(2)
Gene Ontology
(GO)
classifications
All GO classifications: (33 annotations)
Process carbohydrate metabolic process, keratan sulfate biosynthetic process, ...
Component Golgi apparatus, Golgi membrane, ...
Function 1-hydroxypyrene sulfotransferase activity, 1-phenanthrol sulfotransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (110)    Tissues (98)    Images (17)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 110
cDNA source data(8)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(10) cDNA(8) Other(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000031952 (Evidence)
Entrez Gene56773 (Evidence)
UniGene432506
DFCITC1585393
DoTSDT.527549
NIA Mouse Gene IndexU030272
EC2.8.2.-
Consensus CDS ProjectCCDS22682.1
International Mouse Knockout Project StatusChst5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 56773 NCBI Gene Model | MGI Sequence Detail 21065 C57BL/6J ±  kb
transcript NM_019950 RefSeq | MGI Sequence Detail 1935 C57BL/6 
polypeptide Q9QUP4 UniProt | EBI | MGI Sequence Detail 395 Not Applicable 

For the selected sequences
All sequences(14) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(163 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016469 Carbohydrate sulfotransferase
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR000863 Sulfotransferase domain
Protein Ontology PR:000005478 carbohydrate sulfotransferase 5
Graphical View of Protein Domain Structure
References (Earliest) J:57776 Lee JK, et al., Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue. Biochem Biophys Res Commun. 1999 Sep 24;263(2):543-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGI:2142470

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory