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Thap11 Gene Detail
Summary
  • Symbol
    Thap11
  • Name
    THAP domain containing 11
  • Synonyms
    2810036E22Rik, CTG-B45d, Ronin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930964
    NCBI Gene: 59016
Location & Maps
more
  • Sequence Map
    Chr8:105855103-105856950 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1848 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    THAP11, THAP domain containing 11
  • Vertebrate Orthologs
    8
  • Human Ortholog
    THAP11, THAP domain containing 11
    Orthology source: HomoloGene
  • Synonyms
    CTG-B43a, CTG-B45d, HRIHFB2206, RONIN
  • Links
    NCBI Gene ID: 57215
    neXtProt AC: NX_Q96EK4

  • Chr Location
    16q22.1; chr16:67842310-67844195 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Gene trapped
    1
  • Targeted
    3
  • Incidental Mutations
Homozygous inactivation of this gene leads to peri-implantation lethality and defects in the inner cell mass. Homozygous null ES cells are not viable.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 59016 NCBI Gene Model | MGI Sequence Detail 1848 C57BL/6J ±  kb
transcript NM_021513 RefSeq | MGI Sequence Detail 1848 C57BL/6  
polypeptide Q9JJD0 UniProt | EBI | MGI Sequence Detail 305 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000016304 THAP domain-containing protein 11
  • InterPro Domains
    IPR006612 Zinc finger, C2CH-type
Molecular
Reagents
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  • All nucleic 74
    cDNA 72
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924091
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory