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Thap11 Gene Detail
Summary
  • Symbol
    Thap11
  • Name
    THAP domain containing 11
  • Synonyms
    2810036E22Rik, CTG-B45d, Ronin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930964
    NCBI Gene: 59016
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:105855132-105856950 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 53.05 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930964
protein coding gene Chr8:105855103-105856950 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034062
protein coding gene Chr8:108173631-108175478 (+)
A/J MGP_AJ_G0034043
protein coding gene Chr8:103847141-103848988 (+)
AKR/J MGP_AKRJ_G0033969
protein coding gene Chr8:106849112-106850959 (+)
BALB/cJ MGP_BALBcJ_G0034036
protein coding gene Chr8:104035193-104037040 (+)
C3H/HeJ MGP_C3HHeJ_G0033748
protein coding gene Chr8:107592941-107594788 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034556
protein coding gene Chr8:112145520-112147367 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031498
protein coding gene Chr8:96988715-96990568 (+)
CAST/EiJ MGP_CASTEiJ_G0033074
protein coding gene Chr8:107107816-107109663 (+)
CBA/J MGP_CBAJ_G0033721
protein coding gene Chr8:115749789-115751636 (+)
DBA/2J MGP_DBA2J_G0033876
protein coding gene Chr8:103193861-103195708 (+)
FVB/NJ MGP_FVBNJ_G0033822
protein coding gene Chr8:102124685-102126532 (+)
LP/J MGP_LPJ_G0033967
protein coding gene Chr8:108384077-108385924 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033865
protein coding gene Chr8:118944871-118946718 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034574
protein coding gene Chr8:106816200-106818047 (+)
PWK/PhJ MGP_PWKPhJ_G0032775
protein coding gene Chr8:102596934-102598781 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032616
protein coding gene Chr8:105506717-105508564 (+)
WSB/EiJ MGP_WSBEiJ_G0033190
protein coding gene Chr8:107502493-107504340 (+)



Homology
more
  • Human Ortholog
    THAP11, THAP domain containing 11
  • Vertebrate Orthologs
    8
  • Human Ortholog
    THAP11, THAP domain containing 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CTG-B43a, CTG-B45d, HRIHFB2206, RONIN
  • Links
    NCBI Gene ID: 57215
    neXtProt AC: NX_Q96EK4
    UniProt: Q96EK4

  • Chr Location
    16q22.1; chr16:67842310-67844195 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous inactivation of this gene leads to peri-implantation lethality and defects in the inner cell mass. Homozygous null ES cells are not viable.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036442 Ensembl Gene Model | MGI Sequence Detail 1819 C57BL/6J ±  kb
transcript ENSMUST00000040445 Ensembl | MGI Sequence Detail 1819 Not Applicable  
polypeptide ENSMUSP00000048994 Ensembl | MGI Sequence Detail 305 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 76
    cDNA 74
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924091
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:254842 Fujita J, et al., Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs. Cell Rep. 2017 Nov 7;21(6):1562-1573

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory