About   Help   FAQ
Thap11
Gene Detail
Symbol

Name
ID
Thap11
THAP domain containing 11
MGI:1930964
Synonyms
2810036E22Rik, CTG-B45d, Ronin
Feature Type
protein coding gene
Genetic Map
Chromosome 8
53.05 cM, cytoband D2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:105855103-105856950 bp, + strand
From NCBI annotation of GRCm38

  1848 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10726  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Thap11

Human
homologs
Human Homolog THAP11, THAP domain containing 11
NCBI Gene ID 57215
neXtProt AC  NX_Q96EK4
Human Synonyms  CTG-B43a, CTG-B45d, RONIN
Human Chr (Location)  16q22.1; chr16:67842310-67844195 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous inactivation of this gene leads to peri-implantation lethality and defects in the inner cell mass. Homozygous null ES cells are not viable.
 
Interactions
Thap11 interacts with 132 markers (Mir16-1, Mir18, Mir18b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated
Component cytoplasm, intercellular bridge, ...
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (52)    Tissues (18)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
RNA in situ 37
Northern blot 13
cDNA source data(72)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(74) cDNA(72) Primer pair(2)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000036442 (Evidence)
Entrez Gene59016 (Evidence)
UniGene286598
DFCITC1575213
DoTSDT.110887773, DT.110887746, DT.101267987, DT.493175
NIA Mouse Gene IndexU009759
Consensus CDS ProjectCCDS22616.1
International Mouse Knockout Project StatusThap11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 59016 NCBI Gene Model | MGI Sequence Detail 1848 C57BL/6J ±  kb
transcript NM_021513 RefSeq | MGI Sequence Detail 1848 C57BL/6 
polypeptide Q9JJD0 UniProt | EBI | MGI Sequence Detail 305 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(1 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006612 Zinc finger, C2CH-type
Protein Ontology PR:000016304 THAP domain-containing protein 11
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:200454 Ngondo-Mbongo RP, et al., Modulation of gene expression via overlapping binding sites exerted by ZNF143, Notch1 and THAP11. Nucleic Acids Res. 2013 Apr;41(7):4000-14
All references(34)
Other
accession IDs
MGI:1924091

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory