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Thap11
Gene Detail
Symbol

Name
ID
Thap11
THAP domain containing 11
MGI:1930964
Synonyms
2810036E22Rik, CTG-B45d, Ronin
Feature Type
protein coding gene
Genetic Map
Chromosome 8
53.05 cM, cytoband D2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:105855103-105856950 bp, + strand
From NCBI annotation of GRCm38

  1848 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10726  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

HCOP human homology predictions: THAP11
Gene Tree: Thap11

Human
homologs
THAP11, THAP domain containing 11
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 57215
neXtProt AC: NX_Q96EK4

Human Synonyms: CTG-B43a, CTG-B45d, HRIHFB2206, RONIN

Human Chr (Location): 16q22.1; chr16:67842310-67844195 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous inactivation of this gene leads to peri-implantation lethality and defects in the inner cell mass. Homozygous null ES cells are not viable.
 
Interactions
Thap11 interacts with 132 markers (Mir16-1, Mir18, Mir18b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated
Component cytoplasm, intercellular bridge, ...
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (52)    Tissues (18)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
RNA in situ 37
Northern blot 13
cDNA source data(72)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase thap11 ; ZFIN thap11    NEW 
Molecular
reagents
All nucleic(74) cDNA(72) Primer pair(2)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000036442 (Evidence)
Entrez Gene 59016 (Evidence)
UniGene 286598
DFCI TC1575213
DoTS DT.493175, DT.110887773, DT.110887746, DT.101267987
NIA Mouse Gene Index U009759
Consensus CDS Project CCDS22616.1
International Mouse Phenotyping Consortium Status Thap11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 59016 NCBI Gene Model | MGI Sequence Detail 1848 C57BL/6J ±  kb
transcript NM_021513 RefSeq | MGI Sequence Detail 1848 C57BL/6 
polypeptide Q9JJD0 UniProt | EBI | MGI Sequence Detail 305 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(1 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006612 Zinc finger, C2CH-type
Protein Ontology PR:000016304 THAP domain-containing protein 11
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:200454 Ngondo-Mbongo RP, et al., Modulation of gene expression via overlapping binding sites exerted by ZNF143, Notch1 and THAP11. Nucleic Acids Res. 2013 Apr;41(7):4000-14
All references(32)
Other
accession IDs
MGI:1924091

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory