Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including electron transport chain; negative regulation of neuron apoptotic process; and regulation of DNA-templated transcription. Predicted to be located in cytosol. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleoplasm. Is expressed in 1-cell stage embryo; brain ventricular layer; forelimb bud; inferior colliculus; and oocyte. Used to study methylmalonic aciduria and homocystinuria type cblC. Orthologous to human THAP11 (THAP domain containing 11).