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Cyp3a25
Gene Detail
 Symbol
Name
ID
Cyp3a25
cytochrome P450, family 3, subfamily a, polypeptide 25
MGI:1930638
Feature Type protein coding gene
Genetic Map
Chromosome 5
85.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:145977194-146009618 bp, - strand
From VEGA annotation of GRCm38

  32425 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:135775  Vertebrate Homology Class
3 mouse; 1 rat; 1 chimpanzee

Protein SuperFamily: cytochrome P450 CYP3A5
Gene Tree: Cyp3a25

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Cyp3a25 (2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp3a25 interacts with 181 markers (Mir1b, Mir10a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function aromatase activity, heme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)   
Theiler Stages: 10, 18, 22, 23, 25, 28
Assay TypeResults
RNA in situ 94
RT-PCR 12
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) Genomic(1) cDNA(4) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000025089 (Evidence)
Ensembl Gene ModelENSMUSG00000029630 (Evidence)
Entrez Gene56388 (Evidence)
DoTSDT.110656312, DT.489789
EC1.14.14.1
Consensus CDS ProjectCCDS19866.1
International Mouse Knockout Project StatusCyp3a25
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025089 VEGA Gene Model | MGI Sequence Detail 32425 C57BL/6J ±  kb
transcript OTTMUST00000061713 VEGA | MGI Sequence Detail 2000 Not Applicable 
polypeptide OTTMUSP00000030329 VEGA | MGI Sequence Detail 503 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(5) UniProt(4)
Polymorphisms SNPs within 2kb(111 from dbSNP Build 137)    SNPs within 2kb including multiple locations(131)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR008072 Cytochrome P450, E-class, CYP3A
InterPro IPR002402 Cytochrome P450, E-class, group II
Protein Ontology PR:000006244 cytochrome P450 3A25
References (Earliest) J:65712 Dai D, et al., Cloning, sequencing, heterologous expression, and characterization of murine cytochrome P450 3a25*(Cyp3a25), a testosterone 6beta-hydroxylase. J Biochem Mol Toxicol. 2001;15(2):90-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)
Other
accession IDs
MGI:2140847

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory