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Rec8
Gene Detail
Symbol

Name
ID
Rec8
REC8 meiotic recombination protein
MGI:1929645
Synonyms
mrec, Rec8L1
Feature Type
protein coding gene
Genetic Map
Chromosome 14
28.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:55618037-55625395 bp, + strand
From VEGA annotation of GRCm38

  7359 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3768  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

HCOP human homology predictions: REC8
Gene Tree: Rec8

Human
homologs
REC8, REC8 meiotic recombination protein
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9985
neXtProt AC: NX_O95072

Human Synonyms: HR21spB, REC8L1, Rec8p

Human Chr (Location): 14q11.2-q12; chr14:24171853-24180408 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Chemically induced (other)(1) Targeted(5)
Incidental mutations (data from APF )
Interactions
Rec8 interacts with 9 markers (Mir25, Mir127, Mir292, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process chromosome segregation, double-strand break repair via homologous recombination, ...
Component chromosome, chromosome, centromeric region, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (18 records)
Data Summary: Results (281)    Tissues (116)    Images (46)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 279
RT-PCR 2
cDNA source data(16)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rec8    NEW 
Molecular
reagents
All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000027876 (Evidence)
Ensembl Gene Model ENSMUSG00000002324 (Evidence)
Entrez Gene 56739 (Evidence)
UniGene 23149
DFCI TC1585287
DoTS DT.55241097
NIA Mouse Gene Index U015662
Consensus CDS Project CCDS27120.1
International Mouse Phenotyping Consortium Status Rec8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027876 VEGA Gene Model | MGI Sequence Detail 7359 C57BL/6J ±  kb
transcript OTTMUST00000069034 VEGA | MGI Sequence Detail 2184 Not Applicable 
polypeptide OTTMUSP00000035014 VEGA | MGI Sequence Detail 591 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(29 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023093 Rad21/Rec8-like protein, C-terminal
InterPro IPR006909 Rad21/Rec8-like protein, C-terminal, eukaryotic
InterPro IPR006910 Rad21/Rec8-like protein, N-terminal
Protein Ontology PR:000013858 meiotic recombination protein REC8
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:215225 Koubova J, et al., Retinoic acid activates two pathways required for meiosis in mice. PLoS Genet. 2014 Aug;10(8):e1004541
All references(61)
Other
accession IDs
MGI:2145829

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory