Cyp2d22
Gene Detail

Symbol Name ID

Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 MGI:1929474

Synonyms

2D22

Feature Type

protein coding gene

Genetic Map

Chromosome 15

38.57 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr15:82370528-82380260 bp, - strand From Ensembl annotation of GRCm38   9733 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:75003  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 2 cattle; 1 dog

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2d22

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	arachidonic acid metabolic process, dopamine biosynthetic process, ...
Component	cytoplasm, intracellular membrane-bounded organelle
Function	arachidonic acid monooxygenase activity, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)   
Theiler Stages: 10, 18, 22, 23, 25, 28

Assay Type	Results
RNA in situ	94
RT-PCR	12

cDNA source data(97)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(100) cDNA(98) Primer pair(2)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000061740 (Evidence)
Entrez Gene	56448 (Evidence)
UniGene	474216
DFCI	TC1580397, TC1598987
DoTS	DT.101739683, DT.87078384, DT.97413939
NIA Mouse Gene Index	U036451
Consensus CDS Project	CCDS37159.1
International Mouse Knockout Project Status	Cyp2d22

Sequences

Length	Strain/Species
genomic	ENSMUSG00000061740	Ensembl Gene Model | MGI Sequence Detail	9733	C57BL/6J
transcript	ENSMUST00000023083	Ensembl | MGI Sequence Detail	2771	Not Applicable
polypeptide	ENSMUSP00000023083	Ensembl | MGI Sequence Detail	500	Not Applicable

All sequences(26) RefSeq(4) UniProt(2)

Polymorphisms

SNPs(26 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001128	Cytochrome P450
InterPro	IPR017972	Cytochrome P450, conserved site
InterPro	IPR002401	Cytochrome P450, E-class, group I
InterPro	IPR008069	Cytochrome P450, E-class, group I, CYP2D-like

References

(Earliest) J:64806 Blume N, et al., Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells. Arch Biochem Biophys. 2000 Sep 15;381(2):191-204
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(24)