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Cyp2d22 Gene Detail
Summary
  • Symbol
    Cyp2d22
  • Name
    cytochrome P450, family 2, subfamily d, polypeptide 22
  • Synonyms
    2D22
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929474
    NCBI Gene: 56448
  • Member of
    Cyp2d cluster
Location & Maps
more
  • Sequence Map
    Chr15:82370528-82380260 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9733 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 38.57 cM, cytoband E2
  • Mapping Data
    2 experiments
Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Cyp2d22
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061740 Ensembl Gene Model | MGI Sequence Detail 9733 C57BL/6J ±  kb
transcript ENSMUST00000023083 Ensembl | MGI Sequence Detail 2771 Not Applicable  
polypeptide ENSMUSP00000023083 Ensembl | MGI Sequence Detail 500 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    66 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
    IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
Molecular
Reagents
less
  • All nucleic 100
    cDNA 98
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 20
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 3
    Phenotypes 20
  • Earliest
    J:64806 Blume N, et al., Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells. Arch Biochem Biophys. 2000 Sep 15;381(2):191-204
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory