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Cyp2d22
Gene Detail
 Symbol
Name
ID
Member of
Cyp2d22
cytochrome P450, family 2, subfamily d, polypeptide 22
MGI:1929474
Cyp2d cluster
Synonyms 2D22
Feature Type protein coding gene
Genetic Map
Chromosome 15
38.57 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:82370528-82380260 bp, - strand
From Ensembl annotation of GRCm38

  9733 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75003  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 2 cattle; 1 dog

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2d22

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Radiation induced(1) Targeted(2)
Genomic Mutations involving Cyp2d22 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp2d22 interacts with 135 markers (Mir18, Mir19a, Mir25, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process arachidonic acid metabolic process, dopamine biosynthetic process, ...
Component cytoplasm, intracellular membrane-bounded organelle
Function arachidonic acid monooxygenase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)   
Theiler Stages: 10, 18, 22, 23, 25, 28
Assay TypeResults
RNA in situ 94
RT-PCR 12
cDNA source data(97)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(100) cDNA(98) Primer pair(2)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000061740 (Evidence)
Entrez Gene56448 (Evidence)
UniGene474216
DFCITC1580397, TC1598987
DoTSDT.101739683, DT.87078384, DT.97413939
NIA Mouse Gene IndexU036451
Consensus CDS ProjectCCDS37159.1
International Mouse Knockout Project StatusCyp2d22
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061740 Ensembl Gene Model | MGI Sequence Detail 9733 C57BL/6J ±  kb
transcript ENSMUST00000023083 Ensembl | MGI Sequence Detail 2771 Not Applicable 
polypeptide ENSMUSP00000023083 Ensembl | MGI Sequence Detail 500 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(67 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
InterPro IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
References (Earliest) J:64806 Blume N, et al., Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells. Arch Biochem Biophys. 2000 Sep 15;381(2):191-204
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.18
The Jackson Laboratory