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Arpc1a Gene Detail
Summary
  • Symbol
    Arpc1a
  • Name
    actin related protein 2/3 complex, subunit 1A
  • Synonyms
    0610010H08Rik, 1110030K07Rik, Sid32
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928896
    NCBI Gene: 56443
  • Gene Overview
    MyGene.info: ARPC1A
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:145083869-145108756 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 85.00 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928896
protein coding gene Chr5:145083830-145108761 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030355
protein coding gene Chr5:150505319-150530526 (+)
A/J MGP_AJ_G0030324
protein coding gene Chr5:144039833-144065637 (+)
AKR/J MGP_AKRJ_G0030256
protein coding gene Chr5:148512155-148543166 (+)
BALB/cJ MGP_BALBcJ_G0030341
protein coding gene Chr5:145294458-145320273 (+)
C3H/HeJ MGP_C3HHeJ_G0030052
protein coding gene Chr5:149338626-149365674 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030786
protein coding gene Chr5:155995185-156027306 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028007
protein coding gene Chr5:137777902-137801466 (+)
CAST/EiJ MGP_CASTEiJ_G0029457
protein coding gene Chr5:148902917-148933109 (+)
CBA/J MGP_CBAJ_G0030022
protein coding gene Chr5:162431996-162465744 (+)
DBA/2J MGP_DBA2J_G0030172
protein coding gene Chr5:143755478-143780800 (+)
FVB/NJ MGP_FVBNJ_G0030127
protein coding gene Chr5:142988595-143016093 (+)
LP/J MGP_LPJ_G0030261
protein coding gene Chr5:151087919-151116411 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030158
protein coding gene Chr5:164738465-164767020 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030826
protein coding gene Chr5:148413694-148446607 (+)
PWK/PhJ MGP_PWKPhJ_G0029172
protein coding gene Chr5:142904512-142929583 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029008
protein coding gene Chr5:146163561-146193515 (+)
WSB/EiJ MGP_WSBEiJ_G0029532
protein coding gene Chr5:149222063-149250880 (+)



Homology
more
  • Human Ortholog
    ARPC1A, actin related protein 2/3 complex subunit 1A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ARPC1A, actin related protein 2/3 complex subunit 1A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Arc40, HEL-68, HEL-S-307, SOP2Hs, SOP2L
  • Links
    NCBI Gene ID: 10552
    neXtProt AC: NX_Q92747
    UniProt: Q92747

  • Chr Location
    7q22.1; chr7:99325873-99366262 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56443 NCBI Gene Model | MGI Sequence Detail 24888 C57BL/6J ±  kb
transcript NM_019767 RefSeq | MGI Sequence Detail 1588 C57BL/6  
polypeptide Q9R0Q6 UniProt | EBI | MGI Sequence Detail 370 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000004308 actin-related protein 2/3 complex subunit 1A
  • InterPro Domains
    IPR017383 Actin-related protein 2/3 complex subunit 1
    IPR030140 Actin-related protein 2/3 complex subunit 1A
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 227
    cDNA 227

    Microarray probesets 3
Other
Accession IDs
less
MGI:1914685, MGI:1924157, MGI:2140724
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:197772 Baas D, et al., CKIP-1 regulates mammalian and zebrafish myoblast fusion. J Cell Sci. 2012 Aug 15;125(Pt 16):3790-800

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory