Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Arpc1a
actin related protein 2/3 complex, subunit 1A
MGI:1928896

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Click on allele symbol for full phenotype details.

	Caption: Open cranial neural tube in an E9.5 Arpc1a^em1(IMPC)J/Arpc1a^em1(IMPC)J embryo. (details) Represented Alleles: Arpc1a^em1(IMPC)J, actin related protein 2/3 complex, subunit 1A; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: E9.5 Arpc1a^em1(IMPC)J/Arpc1a^em1(IMPC)J embryos have abnormal head shape, sometimes with incomplete cranial neural tube closure, and about half have branchial arch/pouch abnormalities and abnormal cardiac development. E10.5 embryos are dysmorphic or dying. (details) Represented Alleles: Arpc1a^em1(IMPC)J, actin related protein 2/3 complex, subunit 1A; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: Arpc1a^em1(IMPC)J/Arpc1a^em1(IMPC)J (-/-) placentas have an expanded spongiotrophoblast layer, multiple labyrinth zone defects, and nearly absent chorioallantoic branching at E10.5. (details) Represented Alleles: Arpc1a^em1(IMPC)J, actin related protein 2/3 complex, subunit 1A; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: Despite gross abnormalities including an open cranial neural tube and severely dysmorphic head and pericardial edema, all Arpc1a^em1(IMPC)J/Arpc1a^em1(IMPC)J embryos display appropriate germ layer patterning at E10.5. (details) Represented Alleles: Arpc1a^em1(IMPC)J, actin related protein 2/3 complex, subunit 1A; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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