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Hnrnph3 Gene Detail
Summary
  • Symbol
    Hnrnph3
  • Name
    heterogeneous nuclear ribonucleoprotein H3
  • Synonyms
    hnRNP 2H9, Hnrph3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926462
    NCBI Gene: 432467
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:62850443-62859764 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 32.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    235 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926462
 protein coding gene Chr10:62850443-62859996 (-)
129S1/SvImJ ENSMUSG00200027181
 protein coding gene Chr10:59523277-59532829 (-)
A/J ENSMUSG00195026480
 protein coding gene Chr10:59830604-59840157 (-)
AKR/J ENSMUSG00220036756
 protein coding gene Chr10:59523929-59533482 (-)
BALB/cJ ENSMUSG00180025976
 protein coding gene Chr10:59872919-59882471 (-)
C3H/HeJ ENSMUSG00175023265
 protein coding gene Chr10:59730447-59739999 (-)
C57BL/6NJ ENSMUSG00215022767
 protein coding gene Chr10:59471023-59480577 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015396
 protein coding gene Chr10:57508080-57517658 (-)
CAST/EiJ ENSTCUG00005027206
 protein coding gene Chr10:59521891-59531446 (-)
CBA/J ENSMUSG00210033667
 protein coding gene Chr10:59608737-59618289 (-)
DBA/2J ENSMUSG00185039368
 protein coding gene Chr10:59950319-59959871 (-)
FVB/NJ ENSMUSG00205029547
 protein coding gene Chr10:59622401-59631953 (-)
JF1/MsJ ENSUMUG00000017987
 protein coding gene Chr10:61192684-61202233 (-)
LP/J ENSMUSG00230014337
 protein coding gene Chr10:61753185-61762737 (-)
NOD/ShiLtJ ENSMUSG00190027794
 protein coding gene Chr10:59935941-59945493 (-)
NZO/HlLtJ ENSMUSG00225043453
 protein coding gene Chr10:66034235-66043787 (-)
PWK/PhJ ENSLUMG00010021541
 protein coding gene Chr10:59579373-59588922 (-)
SPRET/EiJ ENSMSPG00010021374
 protein coding gene Chr10:61132186-61141729 (-)
WSB/EiJ ENSIUOG00005040696
 protein coding gene Chr10:59516366-59525941 (-)



Homology
more
  • Human Ortholog
    HNRNPH3, heterogeneous nuclear ribonucleoprotein H3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HNRNPH3, heterogeneous nuclear ribonucleoprotein H3
  • Synonyms
    2H9, HNRPH3
  • Links
    NCBI Gene ID: 3189
    UniProt: P31942

  • Chr Location
    10q21.3; chr10:68331174-68344002 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    674
  • Tissues
    33
  • cDNA Data
    13
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 432467 NCBI Gene Model | MGI Sequence Detail 9322 C57BL/6J ±  kb
transcript NM_001079824 RefSeq | MGI Sequence Detail 2170 C57BL/6  
polypeptide NP_001346189 RefSeq | MGI Sequence Detail 346 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR050666 Epithelial Splicing Regulatory
    IPR034970 hnRNPH3, RNA recognition motif 2
    IPR034969 hnRNPH3, RNA recognition motif 3
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:3034530, MGI:3034828
References
more
  • Summaries
    All 37
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:363164 Zhu S, et al., Fine-tuning of Wnt signaling by RNA surveillance factor Smg5 in the mouse craniofacial development. iScience. 2025 Mar 21;28(3):111972
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory