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Hnrnph3 Gene Detail
Summary
  • Symbol
    Hnrnph3
  • Name
    heterogeneous nuclear ribonucleoprotein H3
  • Synonyms
    hnRNP 2H9, Hnrph3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926462
    NCBI Gene: 432467
  • Gene Overview
    MyGene.info: HNRNPH3
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:63014664-63023932 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 32.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    48 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926462
protein coding gene Chr10:63014664-63024217 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017310
protein coding gene Chr10:62507094-62517595 (-)
A/J MGP_AJ_G0017288
protein coding gene Chr10:60565972-60575403 (-)
AKR/J MGP_AKRJ_G0017248
protein coding gene Chr10:62163580-62175271 (-)
BALB/cJ MGP_BALBcJ_G0017248
protein coding gene Chr10:60679938-60689314 (-)
C3H/HeJ MGP_C3HHeJ_G0017071
protein coding gene Chr10:62081765-62092088 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017706
protein coding gene Chr10:64753068-64762529 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015396
protein coding gene Chr10:57508080-57517658 (-)
CAST/EiJ MGP_CASTEiJ_G0016642
protein coding gene Chr10:62131922-62143009 (-)
CBA/J MGP_CBAJ_G0017043
protein coding gene Chr10:67199096-67208540 (-)
DBA/2J MGP_DBA2J_G0017148
protein coding gene Chr10:59838711-59848488 (-)
FVB/NJ MGP_FVBNJ_G0017142
protein coding gene Chr10:59108254-59118360 (-)
LP/J MGP_LPJ_G0017222
protein coding gene Chr10:62876210-62885661 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017170
protein coding gene Chr10:69370491-69379922 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017744
protein coding gene Chr10:62003191-62012636 (-)
PWK/PhJ MGP_PWKPhJ_G0016425
protein coding gene Chr10:59719508-59729133 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016207
protein coding gene Chr10:61355392-61365753 (-)
WSB/EiJ MGP_WSBEiJ_G0016706
protein coding gene Chr10:61958786-61968829 (-)



Homology
more
  • Human Ortholog
    HNRNPH3, heterogeneous nuclear ribonucleoprotein H3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HNRNPH3, heterogeneous nuclear ribonucleoprotein H3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    2H9, HNRPH3
  • Links
    NCBI Gene ID: 3189
    neXtProt AC: NX_P31942
    UniProt: P31942

  • Chr Location
    10q21.3; chr10:68331174-68343196 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 432467 NCBI Gene Model | MGI Sequence Detail 9269 C57BL/6J ±  kb
transcript NM_001079824 RefSeq | MGI Sequence Detail 2170 C57BL/6  
polypeptide NP_001346189 RefSeq | MGI Sequence Detail 346 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR034970 hnRNPH3, RNA recognition motif 2
    IPR034969 hnRNPH3, RNA recognition motif 3
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
less
MGI:3034530, MGI:3034828
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:241665 Cho KI, et al., Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes. Dis Model Mech. 2017 May 01;10(5):559-579

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory