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Arid1b Gene Detail
Summary
  • Symbol
    Arid1b
  • Name
    AT rich interactive domain 1B (SWI-like)
  • Synonyms
    9330189K18Rik, B230217J03Rik, mKIAA1235
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926129
    NCBI Gene: 239985
  • Gene Overview
    MyGene.info: ARID1B
Location & Maps
more
  • Sequence Map
    Chr17:4994332-5347656 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      353325 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ARID1B, AT-rich interaction domain 1B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ARID1B, AT-rich interaction domain 1B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    6A3-5, BAF250B, BRIGHT, CSS1, DAN15, ELD/OSA1, MRD12, OSA2, P250R
  • Links
    NCBI Gene ID: 57492
    neXtProt AC: NX_Q8NFD5

  • Chr Location
    6q25.1; chr6:156777892-157210779 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ARID1B associations

Human Disease Mouse Models
       Coffin-Siris Syndrome 1; CSS1   OMIM: 135900
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    62
  • Gene trapped
    59
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Arid1b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023805 VEGA Gene Model | MGI Sequence Detail 353325 C57BL/6J ±  kb
transcript OTTMUST00000059181 VEGA | MGI Sequence Detail 7150 Not Applicable  
polypeptide OTTMUSP00000028765 VEGA | MGI Sequence Detail 2243 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    2306 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR001606 ARID DNA-binding domain
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR021906 SWI/SNF-like complex subunit BAF250/Osa
Molecular
Reagents
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  • All nucleic 60
    cDNA 60

    Microarray probesets 5
Other
Accession IDs
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MGI:1924763, MGI:2146926
References
more
  • Summaries
    All 35
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:212358 Singh AP, et al., Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation. Nucleic Acids Res. 2014 Mar;42(5):2958-75

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory