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Ak7 Gene Detail
Summary
  • Symbol
    Ak7
  • Name
    adenylate kinase 7
  • Synonyms
    4930502N02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926051
    NCBI Gene: 78801
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr12:105705976-105782447 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      76472 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 55.95 cM, cytoband F1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    AK7, adenylate kinase 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AK7, adenylate kinase 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AK 7
  • Links
    NCBI Gene ID: 122481
    neXtProt AC: NX_Q96M32
    UniProt: Q96M32

  • Chr Location
    14q32.2; chr14:96392111-96489427 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 14268
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: AK7
  • Gene Tree
    Ak7
Human Diseases
more
  • Diseases
    1 with Ak7 mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    16 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mice exhibit hydrocephalus, rhinitis, sperm defects and most die before 8 weeks of age.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041323 Ensembl Gene Model | MGI Sequence Detail 76472 C57BL/6J ±  kb
transcript ENSMUST00000040876 Ensembl | MGI Sequence Detail 3099 Not Applicable  
polypeptide ENSMUSP00000043145 Ensembl | MGI Sequence Detail 723 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    279 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Diseases 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:240319 Stauber M, et al., Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/17/2017
MGI 6.10
The Jackson Laboratory