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Ak7
Gene Detail
Symbol

Name
ID
Ak7
adenylate kinase 7
MGI:1926051
Synonyms
4930502N02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 12
55.95 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:105705982-105782447 bp, + strand
From Ensembl annotation of GRCm38

  76466 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14268  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: AK7
Gene Tree: Ak7

Human
homologs
AK7, adenylate kinase 7
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 122481
neXtProt AC: NX_Q96M32

Human Synonyms: AK 7

Human Chr (Location): 14q32.2; chr14:96392111-96489427 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(182) : Gene trapped(181) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mice exhibit hydrocephalus, rhinitis, sperm defects and most die before 8 weeks of age.
 
Interactions
Ak7 interacts with 113 markers (Mir7-2, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process axoneme assembly, brain development, ...
Component cytoplasm, nucleus
Function adenylate kinase activity, ATP binding, ...
External Resources: FuncBase
Expression
cDNA source data(3)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ak7 ; ZFIN ak7b    NEW 
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000041323 (Evidence)
Entrez Gene 78801 (Evidence)
DFCI TC1589257, TC1596392
DoTS DT.55170228, DT.101717839, DT.101291908
NIA Mouse Gene Index U014347
EC 2.7.4.6, 2.7.4.3
Consensus CDS Project CCDS49162.1
International Mouse Phenotyping Consortium Status Ak7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041323 Ensembl Gene Model | MGI Sequence Detail 76466 C57BL/6J ±  kb
transcript ENSMUST00000040876 Ensembl | MGI Sequence Detail 3093 Not Applicable 
polypeptide ENSMUSP00000043145 Ensembl | MGI Sequence Detail 723 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(7) UniProt(2)
Polymorphisms
SNPs within 2kb(280 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000850 Adenylate kinase
InterPro IPR007858 Dpy-30 motif
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000029118 adenylate kinase 7
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory