Adamtsl2
Gene Detail

Symbol Name ID

Adamtsl2 ADAMTS-like 2 MGI:1925044

Synonyms

A930008K15Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 2

19.22 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr2:27079379-27108981 bp, + strand From VEGA annotation of GRCm38   29603 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:8798  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Adamtsl2

Human homologs

Human Homolog		ADAMTSL2, ADAMTS-like 2
NCBI Gene ID		9719
neXtProt AC		NX_Q86TH1
Human Synonyms		GPHYSD1
Human Chr (Location)		9q34.2; chr9:136397286-136440641 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ADAMTSL2

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	negative regulation of transforming growth factor beta receptor signaling pathway
Component	extracellular matrix, extracellular region, ...
Function	metalloendopeptidase activity, metallopeptidase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (169)    Tissues (55)    Images (24)
Theiler Stages: 10, 11, 18, 23, 24, 25, 28

Assay Type	Results
Immunohistochemistry	16
RNA in situ	141
Northern blot	11
RT-PCR	1

cDNA source data(17)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(19) cDNA(17) Primer pair(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000011845 (Evidence)
Ensembl Gene Model	ENSMUSG00000036040 (Evidence)
Entrez Gene	77794 (Evidence)
UniGene	330088
DFCI	TC1586668, TC1588404, TC1752336
DoTS	DT.103560057, DT.40147919, DT.40148123
NIA Mouse Gene Index	U001530
Consensus CDS Project	CCDS15824.1
International Mouse Knockout Project Status	Adamtsl2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000011845	VEGA Gene Model | MGI Sequence Detail	29603	C57BL/6J
transcript	OTTMUST00000027839	VEGA | MGI Sequence Detail	3612	Not Applicable
polypeptide	OTTMUSP00000012646	VEGA | MGI Sequence Detail	957	Not Applicable

All sequences(35) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(266 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR010294	ADAM-TS Spacer 1
InterPro	IPR013273	Peptidase M12B, ADAM-TS
InterPro	IPR010909	PLAC
InterPro	IPR000884	Thrombospondin, type 1 repeat
Protein Ontology	PR:000003739	ADAMTS-like protein 2

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)