Adamtsl2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adamtsl2
ADAMTS-like 2
MGI:1925044

73 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adamtsl2^stb/Adamtsl2^stb Not Specified	abnormal axial skeleton morphology	J:5109
	abnormal body size	J:5109
	abnormal body weight	J:5109
	abnormal cartilage development	J:5109, J:5669
	abnormal long bone epiphyseal plate morphology	J:5109
	abnormal long bone epiphyseal plate proliferative zone	J:5109
	abnormal sperm number	J:5109
	abnormal trabecular bone morphology	J:5109
	decreased body length	J:5109
	decreased cranium height	J:5109
	decreased length of long bones	J:5109
	decreased long bone epiphyseal plate size	J:5669
	decreased width of hypertrophic chondrocyte zone	J:5109
	disproportionate dwarf	J:5109
	domed cranium	J:5109
	postnatal growth retardation	J:5109
	reduced male fertility	J:5109
	short limbs	J:5109
	short tail	J:5109
	small testis	J:5109
	thick tail	J:5109
Adamtsl2^stb/Adamtsl2^stb STOCK Adamtsl2^stb + a/+ Fign^fi a/J	abnormal intromission	J:346340
	abnormal sexual interaction	J:346340
	failure of ejaculation	J:346340
	impotence	J:346340
	male infertility	J:346340
Adamtsl2^{tm1a(KOMP)Wtsi}/Adamtsl2^{tm1a(KOMP)Wtsi} C57BL/6N-Adamtsl2^{tm1a(KOMP)Wtsi}/MbpMmucd	neonatal lethality, incomplete penetrance	J:345629
	postnatal growth retardation	J:345629
	postnatal lethality, complete penetrance	J:345629
Adamtsl2^{tm1a(KOMP)Wtsi}/Adamtsl2^tm1Mtek involves: C57BL/6N	abnormal cranium morphology	J:345629
	brachyphalangia	J:345629
	normal cardiovascular system phenotype	J:345629
	decreased body weight	J:345629
	normal mortality/aging	J:345629
	short femur	J:345629
Adamtsl2^{tm1a(KOMP)Wtsi}/Adamtsl2^tm2Mtek involves: C57BL/6N	abnormal aortic valve morphology	J:345629
	abnormal atrium myocardium morphology	J:345629
	abnormal cranium morphology	J:345629
	abnormal forced expiratory flow rates	J:345629
	abnormal heart echocardiography feature	J:345629
	abnormal heart valve physiology	J:345629
	abnormal lung morphology	J:345629
	abnormal myocardium layer morphology	J:345629
	abnormal phalanx morphology	J:345629
	abnormal respiratory function	J:345629
	brachyphalangia	J:345629
	cardiac hypertrophy	J:345629
	cardiac interstitial fibrosis	J:345629
	cardiomyopathy	J:345629
	decreased cardiac output	J:345629
	decreased cardiac stroke volume	J:345629
	decreased heart ventricle muscle contractility	J:345629
	lung inflammation	J:345629
	neonatal lethality, incomplete penetrance	J:345629
	premature death	J:345629
	short femur	J:345629
	short nasal bone	J:345629
	short snout	J:345629
	slow postnatal weight gain	J:345629
	supravalvar aortic stenosis	J:345629
Adamtsl2^{tm1b(KOMP)Wtsi}/Adamtsl2^{tm1b(KOMP)Wtsi} C57BL/6-Adamtsl2^{tm1b(KOMP)Wtsi}	abnormal bronchus epithelium morphology	J:221347
	cyanosis	J:221347
	decreased respiration	J:221347
	normal muscle phenotype	J:221347
	neonatal lethality	J:221347
	respiratory distress	J:221347
Adamtsl2^{tm1c(KOMP)Wtsi}/Adamtsl2^{tm1c(KOMP)Wtsi} Tg(Prrx1-cre)1Cjt/0 B6.Cg-Adamtsl2^{tm1c(KOMP)Wtsi} Tg(Prrx1-cre)1Cjt	abnormal autopod morphology	J:280264
	abnormal calcaneal tendon morphology	J:280264
	abnormal limb bone morphology	J:280264
	abnormal long bone diaphysis morphology	J:280264
	abnormal long bone metaphysis morphology	J:280264
	abnormal tendon cell morphology	J:280264
	abnormal tendon collagen fibril morphology	J:280264
	short metatarsal bones	J:280264
	short radius	J:280264
	short tibia	J:280264
Adamtsl2^{tm1c(KOMP)Wtsi}/Adamtsl2^{tm1c(KOMP)Wtsi} Tg(Scx-GFP/cre)1Stzr/0 involves: C57BL/6 * C57BL/6N	abnormal calcaneal tendon morphology	J:280264
	abnormal limb bone morphology	J:280264
	short humerus	J:280264
	short radius	J:280264
	short tibia	J:280264
	short ulna	J:280264
Adamtsl2^tm1Mtek/Adamtsl2^tm1Mtek Not Specified	abnormal cranium morphology	J:345629
	brachyphalangia	J:345629
	normal cardiovascular system phenotype	J:345629
	decreased body weight	J:345629
	normal mortality/aging	J:345629
	short femur	J:345629
Adamtsl2^tm1Mtek/Adamtsl2^tm2Mtek Not Specified	abnormal phalanx morphology	J:345629
	brachyphalangia	J:345629
	normal cardiovascular system phenotype	J:345629
	normal mortality/aging	J:345629
	slow postnatal weight gain	J:345629
Adamtsl2^tm2Mtek/Adamtsl2^tm2Mtek Not Specified	abnormal aortic valve morphology	J:345629
	abnormal atrium myocardium morphology	J:345629
	abnormal cranium morphology	J:345629
	abnormal forced expiratory flow rates	J:345629
	abnormal heart echocardiography feature	J:345629
	abnormal lung morphology	J:345629
	abnormal myocardium layer morphology	J:345629
	abnormal respiratory function	J:345629
	brachyphalangia	J:345629
	cardiac hypertrophy	J:345629
	cardiac interstitial fibrosis	J:345629
	cardiomyopathy	J:345629
	lung inflammation	J:345629
	neonatal lethality, incomplete penetrance	J:345629
	short femur	J:345629
	short nasal bone	J:345629
	short snout	J:345629
	slow postnatal weight gain	J:345629

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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