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Mrps5 Gene Detail
Summary
  • Symbol
    Mrps5
  • Name
    mitochondrial ribosomal protein S5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924971
    NCBI Gene: 77721
  • Gene Overview
    MyGene.info: MRPS5
Location & Maps
more
  • Sequence Map
    Chr2:127587222-127606829 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19608 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 62.05 cM, cytoband F3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    MRPS5, mitochondrial ribosomal protein S5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MRPS5, mitochondrial ribosomal protein S5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MRP-S5, S5mt
  • Links
    NCBI Gene ID: 64969
    neXtProt AC: NX_P82675

  • Chr Location
    2p11.2-q11.2; chr2:95087207-95122009 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    40
  • Chemically induced (other)
    1
  • Gene trapped
    33
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Mrps5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016028 VEGA Gene Model | MGI Sequence Detail 19608 C57BL/6J ±  kb
transcript OTTMUST00000038212 VEGA | MGI Sequence Detail 4481 Not Applicable  
polypeptide OTTMUSP00000017134 VEGA | MGI Sequence Detail 432 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    263 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010643 28S ribosomal protein S5, mitochondrial
  • InterPro Domains
    IPR014720 Double-stranded RNA-binding domain
    IPR000851 Ribosomal protein S5
    IPR005324 Ribosomal protein S5, C-terminal
    IPR020568 Ribosomal protein S5 domain 2-type fold
    IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup
    IPR013810 Ribosomal protein S5, N-terminal
    IPR018192 Ribosomal protein S5, N-terminal, conserved site
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 8
Other
Accession IDs
less
MGI:2139078
References
more
  • Summaries
    All 38
    Gene Ontology 6
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:198736 Houtkooper RH, et al., Mitonuclear protein imbalance as a conserved longevity mechanism. Nature. 2013 May 23;497(7450):451-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory