Mrps5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mrps5
mitochondrial ribosomal protein S5
MGI:1924971

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mrps5^{tm1b(EUCOMM)Wtsi}/Mrps5⁺ C57BL/6N-Mrps5^{tm1b(EUCOMM)Wtsi}/Wtsi	decreased grip strength	J:211773
Mrps5^{tm1b(EUCOMM)Wtsi}/Mrps5^{tm1b(EUCOMM)Wtsi} C57BL/6N-Mrps5^{tm1b(EUCOMM)Wtsi}/Wtsi	embryonic lethality prior to organogenesis	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Mrps5^tm2.2Dshc/Mrps5⁺ involves: 129 * C57BL/6	no abnormal phenotype detected	J:267202
Mrps5^tm2.2Dshc/Mrps5^tm2.2Dshc involves: 129 * C57BL/6	abnormal learning/memory/conditioning	J:267202
	abnormal mitochondrial ATP synthesis coupled electron transport	J:267202
	abnormal mitochondrial physiology	J:267202
	abnormal oxidative phosphorylation	J:267202
	abnormal respiratory electron transport chain	J:267202
	normal behavior/neurological phenotype	J:267202
	decreased exploration in new environment	J:267202
	impaired spatial learning	J:267202
	increased anxiety-related response	J:267202
	increased susceptibility to noise-induced hearing loss	J:267202
	normal nervous system phenotype	J:267202
	oxidative stress	J:267202

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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