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Kcnq5
Gene Detail
 Symbol
Name
ID
Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
MGI:1924937
Synonyms 9230107O05Rik, D1Mgi1
Feature Type protein coding gene
Genetic Map
Chromosome 1
6.67 cM, cytoband A5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:21398403-21961942 bp, - strand
From VEGA annotation of GRCm38

  563540 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:28270  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: potassium voltage-gated channel, subfamily KQT
Gene Tree: Kcnq5

Human
homologs
Human Homolog KCNQ5, potassium voltage-gated channel, KQT-like subfamily, member 5
NCBI Gene ID 56479
neXtProt AC  NX_Q9NR82
Human Synonyms  Kv7.5
Human Chr (Location)  6q14; chr6:72621843-73198851 (+)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
 
Mice homozygous for a dominant negative knock-in mutation in this gene exhibit partial prenatal lethality and abnormal afterhyperpolarization in the in the CA3 area of hippocampus.
 
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function delayed rectifier potassium channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (2)   
Theiler Stages: 25, 28
Assay TypeResults
RT-PCR 3
cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(8) cDNA(7) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000019675 (Evidence)
Ensembl Gene ModelENSMUSG00000028033 (Evidence)
Entrez Gene226922 (Evidence)
DFCITC1597588, TC1634911, TC1637887, TC1645078, TC1734972
DoTSDT.101718865, DT.484584, DT.60103390, DT.97357763
NIA Mouse Gene IndexU021168
Consensus CDS ProjectCCDS35525.1, CCDS48230.1
International Mouse Knockout Project StatusKcnq5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019675 VEGA Gene Model | MGI Sequence Detail 563540 C57BL/6J ±  kb
transcript OTTMUST00000047088 VEGA | MGI Sequence Detail 6975 Not Applicable 
polypeptide OTTMUSP00000021274 VEGA | MGI Sequence Detail 952 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(6) UniProt(7)
Polymorphisms SNPs within 2kb(5487 from dbSNP Build 137)    SNPs within 2kb including multiple locations(5493)
Protein-related
information
ResourceIDDescription
InterPro IPR005821 Ion transport domain
InterPro IPR003937 Potassium channel, voltage dependent, KCNQ
InterPro IPR013821 Potassium channel, voltage dependent, KCNQ, C-terminal
InterPro IPR003091 Voltage-dependent potassium channel
Protein Ontology PR:000000732 voltage-gated potassium channel subunit KCNQ5
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:197837 Spitzmaul G, et al., Vestibular role of KCNQ4 and KCNQ5 K+ channels revealed by mouse models. J Biol Chem. 2013 Mar 29;288(13):9334-44
All references(38)
Other
accession IDs
MGI:2138116

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory