Mboat7
Gene Detail

Symbol Name ID

Mboat7 membrane bound O-acyltransferase domain containing 7 MGI:1924832

Synonyms

5730589L02Rik, Leng4, mBB1

Feature Type

protein coding gene

Genetic Map

Chromosome 7

2.12 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:3677790-3693523 bp, - strand From VEGA annotation of GRCm38   15734 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:11510  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Mboat7

Human homologs

Human Homolog		MBOAT7, membrane bound O-acyltransferase domain containing 7
NCBI Gene ID		79143
neXtProt AC		NX_Q96N66
Human Synonyms		BB1, hMBOA-7, LENG4, LPIAT, LRC4, MBOA7, OACT7
Human Chr (Location)		19q13.4; chr19:54677106-54693733 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(3) Gene trapped(2)
 

Mice homozygous for a targeted mutation exhibit hydrocephaly and most die between 1-3 months of age.

 

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	lipid metabolic process, phospholipid biosynthetic process, ...
Component	integral to membrane, membrane
Function	transferase activity, transferase activity, transferring acyl groups

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (117)    Tissues (97)    Images (29)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	117

cDNA source data(117)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(117) cDNA(117)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000023042 (Evidence)
Ensembl Gene Model	ENSMUSG00000035596 (Evidence)
Entrez Gene	77582 (Evidence)
UniGene	482149
DFCI	TC1572281, TC1601165, TC1605422, TC1615555, TC1752152
DoTS	DT.101139328, DT.101157164, DT.101390645, DT.101719249, DT.490593, DT.91426864, DT.94259919
NIA Mouse Gene Index	U028073
EC	2.3.1.-
Consensus CDS Project	CCDS20724.1
International Mouse Knockout Project Status	Mboat7

Sequences

Length	Strain/Species
genomic	OTTMUSG00000023042	VEGA Gene Model | MGI Sequence Detail	15734	C57BL/6J
transcript	OTTMUST00000055526	VEGA | MGI Sequence Detail	2877	Not Applicable
polypeptide	OTTMUSP00000026598	VEGA | MGI Sequence Detail	473	Not Applicable

All sequences(67) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(87 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004299	Membrane bound O-acyl transferase, MBOAT
Protein Ontology	PR:000010227	lysophospholipid acyltransferase 7

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
All references(34)