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Mboat7
Gene Detail
Symbol

Name
ID
Mboat7
membrane bound O-acyltransferase domain containing 7
MGI:1924832
Synonyms
5730589L02Rik, Leng4, Lpiat1, mBB1
Feature Type
protein coding gene
Genetic Map
Chromosome 7
2.12 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:3677790-3693523 bp, - strand
From VEGA annotation of GRCm38

  15734 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11510  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Mboat7

Human
homologs
Human Homolog MBOAT7, membrane bound O-acyltransferase domain containing 7
NCBI Gene ID 79143
neXtProt AC  NX_Q96N66
Human Synonyms  BB1, hMBOA-7, LENG4, LPIAT, LRC4, MBOA7, OACT7
Human Chr (Location)  19q13.4; chr19:54173412-54189882 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted mutation exhibit hydrocephaly and most die between 1-3 months of age. Mice homozygous for a knock-out allele exhibit partial lethality with decreased body size, decreased forebrain size, delayed neuronal migrationand reduced neurite outgrowth.
 
Interactions
Mboat7 interacts with 237 markers (Mir7-1, Mir7-2, Mir7b, ...)
Expression
Literature Summary: (3 records)
Data Summary: Results (117)    Tissues (97)    Images (29)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 117
cDNA source data(121)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(121) cDNA(121)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000023042 (Evidence)
Ensembl Gene ModelENSMUSG00000035596 (Evidence)
Entrez Gene77582 (Evidence)
UniGene397541
DFCITC1572281, TC1601165, TC1605422, TC1615555, TC1752152
DoTSDT.101139328, DT.101157164, DT.101390645, DT.101719249, DT.490593, DT.91426864, DT.94259919
NIA Mouse Gene IndexU028073
EC2.3.1.-
Consensus CDS ProjectCCDS20724.1
International Mouse Knockout Project StatusMboat7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023042 VEGA Gene Model | MGI Sequence Detail 15734 C57BL/6J ±  kb
transcript OTTMUST00000055526 VEGA | MGI Sequence Detail 2877 Not Applicable 
polypeptide OTTMUSP00000026598 VEGA | MGI Sequence Detail 473 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(138 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004299 Membrane bound O-acyl transferase, MBOAT
Protein Ontology PR:000010227 lysophospholipid acyltransferase 7
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:199847 Anderson KE, et al., Lysophosphatidylinositol-acyltransferase-1 (LPIAT1) is required to maintain physiological levels of PtdIns and PtdInsP(2) in the mouse. PLoS One. 2013;8(3):e58425
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory